Bacopa monnieri, a Neuroprotective Lead in Alzheimer Disease: A Review on Its Properties, Mechanisms of Action, and Preclinical and Clinical Studies

AS Abdul Manap, S Vijayabalan… - Drug target …, 2019 - journals.sagepub.com
Alzheimer disease is a neurodegenerative disease that is signified by cognitive decline,
memory loss, and erratic behavior. Till date, no cure for Alzheimer exists and the current …

Metal ions influx is a double edged sword for the pathogenesis of Alzheimer's disease

P Wang, ZY Wang - Ageing Research Reviews, 2017 - Elsevier
Alzheimer's disease (AD) is a common form of dementia in aged people, which is defined by
two pathological characteristics: β-amyloid protein (Aβ) deposition and tau …

Neuroprotective effect of berberine against environmental heavy metals-induced neurotoxicity and Alzheimer's-like disease in rats

HM Hussien, A Abd-Elmegied, DA Ghareeb… - Food and chemical …, 2018 - Elsevier
Heavy metals are reported as neurodegenerative disorders progenitor. They play a role in
the precipitation of abnormal β-amyloid protein and hyper-phosphorylated tau, the main …

[HTML][HTML] Gallic acid and hesperidin elevate neurotransmitters level and protect against oxidative stress, inflammation and apoptosis in aluminum chloride-induced …

BE Ekundayo, TO Obafemi, BA Afolabi… - Pharmacological …, 2022 - Elsevier
Abstract Background/Aim Gallic acid and metformin are plant-derived compounds with
biological effects. The present study aimed to evaluate the protective effect of gallic acid and …

Modified Low-Temperature Extraction Method for Isolation of Bletilla striata Polysaccharide as Antioxidant for the Prevention of Alzheimer's Disease

YW Lin, CH Fang, YJ Liang, HH Liao… - International Journal of …, 2021 - mdpi.com
Amyloid-β (Aβ) peptides play a key role in Alzheimer's disease (AD), the most common type
of dementia. In this study, a polysaccharide from Bletilla striata (BSP), with strong antioxidant …

Molecular and Functional Characterization of Bacopa monniera: A Retrospective Review

KE Rajan, J Preethi, HK Singh - … ‐Based Complementary and …, 2015 - Wiley Online Library
Over the last 50 years, laboratories around the world analyzed the pharmacological effect of
Bacopa monniera extract in different dimensions, especially as a nerve tonic and memory …

[HTML][HTML] Evaluation of acute and chronic effects of D-galactose on memory and learning in Wistar rats

B Chogtu, A Arivazhahan, SK Kunder… - Clinical …, 2018 - ncbi.nlm.nih.gov
Objective D-galactose has been commonly used in rodent models to induce accelerated
effects of aging, including those on learning, memory, and muscular tone and coordination …

Effect of sacubitril/valsartan on cognitive impairment in colchicine‐induced Alzheimer's model in rats

SH Hammadi, MA Hassan, EA Allam… - Fundamental & …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is a complex neurodegenerative disease. There is
epidemiological evidence that heart failure (HF) patients are at higher risk of developing AD …

Clopidogrel combats neuroinflammation and enhances learning behavior and memory in a rat model of Alzheimer's disease

NEA Khalaf, FM El Banna, MY Youssef… - Pharmacology …, 2020 - Elsevier
Background and aim Alzheimer's disease (AD) is a progressive neurodegenerative disease.
Multiple molecular mechanisms have been employed in its pathogenesis such as Amyloid β …

Bio-guided isolation of anti-Alzheimer's compounds from Phyllanthus niruri and role of niruriflavone in the reversal of aluminum chloride-induced neurobehavioral …

G Rajamanickam, M SL - Medicinal Chemistry Research, 2022 - Springer
Alzheimer's disease (AD) is one of the chronic neurodegenerative pathologies that lead to
memory loss and mental and behavioral changes in elderly people. The senile plaques …