[HTML][HTML] Effects of COVID-19 on the nervous system
Neurological complications have emerged as a significant cause of morbidity and mortality
in the ongoing COVID-19 pandemic. Beside respiratory insufficiency, many hospitalized …
in the ongoing COVID-19 pandemic. Beside respiratory insufficiency, many hospitalized …
Immune responses during COVID-19 infection
C Melenotte, A Silvin, AG Goubet, I Lahmar… - …, 2020 - Taylor & Francis
Over the past 16 years, three coronaviruses (CoVs), severe acute respiratory syndrome CoV
(SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and …
(SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and …
A neutrophil activation signature predicts critical illness and mortality in COVID-19
Pathologic immune hyperactivation is emerging as a key feature of critical illness in COVID-
19, but the mechanisms involved remain poorly understood. We carried out proteomic …
19, but the mechanisms involved remain poorly understood. We carried out proteomic …
Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity
Dendritic cells (DCs) and monocytes are crucial mediators of innate and adaptive immune
responses during viral infection, but misdirected responses by these cells may contribute to …
responses during viral infection, but misdirected responses by these cells may contribute to …
Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19
Dysregulated immune responses against the SARS-CoV-2 virus are instrumental in severe
COVID-19. However, the immune signatures associated with immunopathology are poorly …
COVID-19. However, the immune signatures associated with immunopathology are poorly …
Deciphering the state of immune silence in fatal COVID-19 patients
Since the beginning of the SARS-CoV-2 pandemic, COVID-19 appeared as a unique
disease with unconventional tissue and systemic immune features. Here we show a COVID …
disease with unconventional tissue and systemic immune features. Here we show a COVID …
A new haematocytometric index: Predicting severity and mortality risk value in COVID-19 patients
M Kilercik, Ö Demirelce, MA Serdar, P Mikailova… - PloS one, 2021 - journals.plos.org
Introduction Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 virus, is a major
public health concern spanning from healthy carriers to patients with life-threatening …
public health concern spanning from healthy carriers to patients with life-threatening …
Profiling of immune dysfunction in COVID-19 patients allows early prediction of disease progression
With a rising incidence of COVID-19–associated morbidity and mortality worldwide, it is
critical to elucidate the innate and adaptive immune responses that drive disease severity …
critical to elucidate the innate and adaptive immune responses that drive disease severity …
Self-supervised contrastive learning for integrative single cell RNA-seq data analysis
We present a novel self-supervised Contrastive LEArning framework for single-cell
ribonucleic acid (RNA)-sequencing (CLEAR) data representation and the downstream …
ribonucleic acid (RNA)-sequencing (CLEAR) data representation and the downstream …
Immunesenescence: a predisposing risk factor for the development of COVID-19?
J Hazeldine, JM Lord - Frontiers in immunology, 2020 - frontiersin.org
Bearing a strong resemblance to the phenotypic and functional remodeling of the immune
system that occurs during aging (termed immunesenescence), the immune response to …
system that occurs during aging (termed immunesenescence), the immune response to …