Design of bone scaffolds with calcium phosphate and its derivatives by 3D printing: A review
Tissue engineering is a fascinating field that combines biology, engineering, and medicine
to create artificial tissues and organs. It involves using living cells, biomaterials, and …
to create artificial tissues and organs. It involves using living cells, biomaterials, and …
Genetically engineered loaded extracellular vesicles for drug delivery
Z Erana-Perez, M Igartua, E Santos-Vizcaino… - Trends in …, 2024 - cell.com
The use of extracellular vesicles (EVs) for drug delivery is being widely explored by
scientists from several research fields. To fully exploit their therapeutic potential, multiple …
scientists from several research fields. To fully exploit their therapeutic potential, multiple …
Engineered extracellular vesicles enable high-efficient delivery of intracellular therapeutic proteins
D Ma, A Xie, J Lv, X Min, X Zhang, Q Zhou, D Gao… - Protein & …, 2024 - academic.oup.com
Developing an intracellular delivery system is of key importance in the expansion of protein-
based therapeutics acting on cytosolic or nuclear targets. Recently, extracellular vesicles …
based therapeutics acting on cytosolic or nuclear targets. Recently, extracellular vesicles …
Immunogenicity of Extracellular Vesicles
Extracellular vesicles (EVs) are promising next‐generation therapeutics and drug delivery
systems due to demonstrated safety and efficacy in preclinical models and early‐stage …
systems due to demonstrated safety and efficacy in preclinical models and early‐stage …
Inter‐laboratory multiplex bead‐based surface protein profiling of MSC‐derived EV preparations identifies MSC‐EV surface marker signatures
VVT Nguyen, JA Welsh, T Tertel, A Choo… - Journal of …, 2024 - Wiley Online Library
Mesenchymal stromal cells (MSCs) are promising regenerative therapeutics that primarily
exert their effects through secreted extracellular vesicles (EVs). These EVs–being small and …
exert their effects through secreted extracellular vesicles (EVs). These EVs–being small and …
Extracellular Vesicle Spherical Nucleic Acids
H Chen, Q Ding, L Li, P Wei, Z Niu, T Kong, P Fu… - JACS Au, 2024 - ACS Publications
Extracellular vesicles (EVs) are naturally occurring vesicles secreted by cells that can
transport cargo between cells, making them promising bioactive nanomaterials. However …
transport cargo between cells, making them promising bioactive nanomaterials. However …
Tailored apoptotic vesicles promote bone regeneration by releasing the osteoinductive brake
Y Cheng, Y Zhu, Y Liu, X Liu, Y Ding, D Li… - International Journal of …, 2024 - nature.com
Accumulating evidence has demonstrated that apoptotic vesicles (apoVs) derived from
mesenchymal stem cells (MSCs; MSC-apoVs) are vital for bone regeneration, and possess …
mesenchymal stem cells (MSCs; MSC-apoVs) are vital for bone regeneration, and possess …
[HTML][HTML] Antigen-display exosomes provide adjuvant-free protection against SARS-CoV-2 disease at nanogram levels of spike protein
As the only bionormal nanovesicle, exosomes have high potential as a nanovesicle for
delivering vaccines and therapeutics. We show here that the loading of type-1 membrane …
delivering vaccines and therapeutics. We show here that the loading of type-1 membrane …
Mesenchymal stromal cell-derived extracellular vesicles therapy openings new translational challenges in immunomodulating acute liver inflammation
A Sitbon, PR Delmotte, V Pistorio, S Halter… - Journal of Translational …, 2024 - Springer
Inflammation plays a critical role in conditions such as acute liver failure, acute-on-chronic
liver failure, and ischemia–reperfusion-induced liver injury. Various pathogenic pathways …
liver failure, and ischemia–reperfusion-induced liver injury. Various pathogenic pathways …
Defining tropism and activity of natural and engineered extracellular vesicles
Extracellular vesicles (EVs) have important roles as mediators of cell-to-cell communication,
with physiological functions demonstrated in various in vivo models. Despite advances in …
with physiological functions demonstrated in various in vivo models. Despite advances in …