Integrating multi-omics data with EHR for precision medicine using advanced artificial intelligence
With the recent advancement of novel biomedical technologies such as high-throughput
sequencing and wearable devices, multi-modal biomedical data ranging from multi-omics …
sequencing and wearable devices, multi-modal biomedical data ranging from multi-omics …
Current and prospective computational approaches and challenges for developing COVID-19 vaccines
Abstract SARS-CoV-2, which causes COVID-19, was first identified in humans in late 2019
and is a coronavirus which is zoonotic in origin. As it spread around the world there has …
and is a coronavirus which is zoonotic in origin. As it spread around the world there has …
ChromoMap: an R package for interactive visualization of multi-omics data and annotation of chromosomes
L Anand, CM Rodriguez Lopez - BMC bioinformatics, 2022 - Springer
Background The recent advancements in high-throughput sequencing have resulted in the
availability of annotated genomes, as well as of multi-omics data for many living organisms …
availability of annotated genomes, as well as of multi-omics data for many living organisms …
SARS-CoV-2 genomes from Saudi Arabia implicate nucleocapsid mutations in host response and increased viral load
Monitoring SARS-CoV-2 spread and evolution through genome sequencing is essential in
handling the COVID-19 pandemic. Here, we sequenced 892 SARS-CoV-2 genomes …
handling the COVID-19 pandemic. Here, we sequenced 892 SARS-CoV-2 genomes …
Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …
[HTML][HTML] A multi-tissue study of immune gene expression profiling highlights the key role of the nasal epithelium in COVID-19 severity
A Gómez-Carballa, I Rivero-Calle, J Pardo-Seco… - Environmental …, 2022 - Elsevier
Abstract Coronavirus Disease-19 (COVID-19) symptoms range from mild to severe illness;
the cause for this differential response to infection remains unknown. Unravelling the …
the cause for this differential response to infection remains unknown. Unravelling the …
IFI44 is an immune evasion biomarker for SARS-CoV-2 and Staphylococcus aureus infection in patients with RA
Q Zheng, D Wang, R Lin, Q Lv, W Wang - Frontiers in immunology, 2022 - frontiersin.org
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a
global pandemic of severe coronavirus disease 2019 (COVID-19). Staphylococcus aureus is …
global pandemic of severe coronavirus disease 2019 (COVID-19). Staphylococcus aureus is …
Mucosal immunity to severe acute respiratory syndrome coronavirus 2 infection
J Fröberg, DA Diavatopoulos - Current opinion in infectious …, 2021 - journals.lww.com
Although most clinical studies focus on antibodies and cellular immunity in peripheral blood,
mucosal immune responses in the respiratory tract play a key role in the early restriction of …
mucosal immune responses in the respiratory tract play a key role in the early restriction of …
Cytokine storm in the pathophysiology of COVID-19: Possible functional disturbances of miRNAs
Abstract SARS-CoV-2, as the causative agent of COVID-19, is an enveloped positives-sense
single-stranded RNA virus that belongs to the Beta-CoVs sub-family. A sophisticated hyper …
single-stranded RNA virus that belongs to the Beta-CoVs sub-family. A sophisticated hyper …
Considerations for novel COVID-19 mucosal vaccine development
W Alturaiki - Vaccines, 2022 - mdpi.com
Mucosal surfaces are the first contact sites of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). Most SARS-CoV-2 vaccines induce specific IgG responses …
coronavirus 2 (SARS-CoV-2). Most SARS-CoV-2 vaccines induce specific IgG responses …