Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Pathogenicity and virulence of Aspergillus fumigatus

K Earle, C Valero, DP Conn, G Vere, PC Cook… - Virulence, 2023 - Taylor & Francis
Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …

Solid-state NMR molecular snapshots of Aspergillus fumigatus cell wall architecture during a conidial morphotype transition

G Lamon, A Lends, I Valsecchi… - Proceedings of the …, 2023 - National Acad Sciences
While establishing an invasive infection, the dormant conidia of Aspergillus fumigatus transit
through swollen and germinating stages, to form hyphae. During this morphotype transition …

Microbial functional amyloids serve diverse purposes for structure, adhesion and defence

N Shanmugam, MODG Baker, SR Ball, M Steain… - Biophysical …, 2019 - Springer
The functional amyloid state of proteins has in recent years garnered much attention for its
role in serving crucial and diverse biological roles. Amyloid is a protein fold characterised by …

[HTML][HTML] Metal nanomaterials and hydrolytic enzyme-based formulations for improved antifungal activity

I Lyagin, A Aslanli, M Domnin, N Stepanov… - International Journal of …, 2023 - mdpi.com
Active research of metal-containing compounds and enzymes as effective antifungal agents
is currently being conducted due to the growing antifungal resistance problem. Metals are …

[HTML][HTML] Novel treatment approach for aspergilloses by targeting germination

K Verburg, J van Neer, M Duca, H de Cock - Journal of Fungi, 2022 - mdpi.com
Germination of conidia is an essential process within the Aspergillus life cycle and plays a
major role during the infection of hosts. Conidia are able to avoid detection by the majority of …

Modern biophysics redefines our understanding of fungal cell wall structure, complexity, and dynamics

JP Latgé, T Wang - Mbio, 2022 - Am Soc Microbiol
Even though the cell wall has been recognized as a crucial protective organelle for fungi,
essential for its virulence and a unique emblem of this kingdom, biosynthesis of this …

Hydrophobin rodlets on the fungal cell wall

SR Ball, AH Kwan, M Sunde - The fungal cell wall: an armour and a …, 2020 - Springer
The conidia of airborne fungi are protected by a hydrophobic protein layer that coats the cell
wall polysaccharides and renders the spores resistant to wetting and desiccation. A similar …

Cell wall of Aspergillus fumigatus: Variability and response to stress

JP Latge - Fungal Biology, 2023 - Elsevier
The fungal cell is surrounded by a thick cell wall which obviously play an essential role in
the protection of the fungus against external aggressive environments. In spite of 50 years of …

[HTML][HTML] Aspergillus Hydrophobins: Physicochemical Properties, Biochemical Properties, and Functions in Solid Polymer Degradation

T Tanaka, Y Terauchi, A Yoshimi, K Abe - Microorganisms, 2022 - mdpi.com
Hydrophobins are small amphipathic proteins conserved in filamentous fungi. In this review,
the properties and functions of Aspergillus hydrophobins are comprehensively discussed on …