[HTML][HTML] Smart magnetic resonance imaging-based theranostics for cancer

B Brito, TW Price, J Gallo, M Bañobre-López… - Theranostics, 2021 - ncbi.nlm.nih.gov
Smart theranostics are dynamic platforms that integrate multiple functions, including at least
imaging, therapy, and responsiveness, in a single agent. This review showcases a variety of …

Zinc and diabetes

P Chabosseau, GA Rutter - Archives of biochemistry and biophysics, 2016 - Elsevier
Zn 2+ ions are essential for the normal processing and storage of insulin and altered
pancreatic insulin content is associated with all forms of diabetes mellitus. Work of the past …

Highly selective and sensitive turn-on fluorescent sensor for detection of Al3+ based on quinoline-base Schiff base

Y Wang, ZY Ma, DL Zhang, JL Deng, X Chen… - … Acta Part A: Molecular …, 2018 - Elsevier
A new aluminum ion fluorescent probe (4-(diethylamino)-2-hydroxybenzylidene)
isoquinoline-1-carbohydrazide (HL 1) has been conveniently synthesized and …

Responsive gadolinium (III) complex-based small molecule magnetic resonance imaging probes: Design, mechanism and application

Q Meng, M Wu, Z Shang, Z Zhang, R Zhang - Coordination Chemistry …, 2022 - Elsevier
Magnetic resonance imaging (MRI) is a molecular imaging technology that has been widely
adopted in biomedical and clinical diagnostics fields owing to its capability of deep tissue …

Imaging Insulin Secretion from Mouse Pancreas by MRI Is Improved by Use of a Zinc-Responsive MRI Sensor with Lower Affinity for Zn2+ Ions

AF Martins, V Clavijo Jordan, F Bochner… - Journal of the …, 2018 - ACS Publications
It has been demonstrated that divalent zinc ions packaged with insulin in β-cell granules can
be detected by MRI during glucose-stimulated insulin secretion using a gadolinium-based …

Intracellular zinc in insulin secretion and action: a determinant of diabetes risk?

GA Rutter, P Chabosseau, EA Bellomo… - Proceedings of the …, 2016 - cambridge.org
Zinc is an important micronutrient, essential in the diet to avoid a variety of conditions
associated with malnutrition such as diarrhoea and alopecia. Lowered circulating levels of …

A dual functional turn-on non-toxic chemosensor for highly selective and sensitive visual detection of Mg 2+ and Zn 2+: The solvent-controlled recognition effect and …

Y Wang, ZG Wang, XQ Song, Q Chen, H Tian, CZ Xie… - Analyst, 2019 - pubs.rsc.org
A new dual functional turn-on chemosensor, 2, 6-diformyl-4-methylphenol-di (isoquinolinyl-1-
hydrazone)(HL), has been developed, which could highly selectively discriminate Mg2+ and …

Mn (ii) complex impregnated porous silica nanoparticles as Zn (ii)-responsive “Smart” MRI contrast agent for pancreas imaging

R Mallik, M Saha, V Singh, H Mohan… - Journal of Materials …, 2023 - pubs.rsc.org
Type-1 and type-2 diabetes mellitus are metabolic disorders governed by the functional
efficiency of pancreatic β-cells. The activities of the cells toward insulin production, storage …

Molecular imaging of β-cells: diabetes and beyond

W Wei, EB Ehlerding, X Lan, QY Luo, W Cai - Advanced drug delivery …, 2019 - Elsevier
Since diabetes is becoming a global epidemic, there is a great need to develop early β-cell
specific diagnostic techniques for this disorder. There are two types of diabetes (ie, type 1 …

Comparing strategies in the design of responsive contrast agents for magnetic resonance imaging: a case study with copper and zinc

VC Pierre, SM Harris, SL Pailloux - Accounts of Chemical …, 2018 - ACS Publications
Conspectus Magnetic resonance imaging (MRI) has emerged over the years as one of the
preferred modalities for medical diagnostic and biomedical research. It has the advantage …