IL-7: comprehensive review

H Winer, GOL Rodrigues, JA Hixon, FB Aiello, TC Hsu… - Cytokine, 2022 - Elsevier
Overview IL-7 is a member of the family of cytokines with four anti-parallel α helixes that bind
Type I cytokine receptors. It is produced by stromal cells and is required for development …

Immunological aspects of rabies: a literature review

ISS Katz, F Guedes, ER Fernandes… - Archives of …, 2017 - Springer
Rabies is a lethal disease caused by the neurotropic virus rabies virus (RABV), and it
remains an important public health problem globally. It is known that the host immune …

Aptamer and RVG functionalized gold nanorods for targeted photothermal therapy of neurotropic virus infection in the mouse brain

M Ren, J Zhou, Z Song, H Mei, M Zhou, ZF Fu… - Chemical Engineering …, 2021 - Elsevier
The infection of the neurotropic virus damages the central nervous system (CNS) and often
leads to humans' fatal symptoms. Rabies is a lethal disease caused by a typical neurotropic …

Monophosphoryl-lipid A (MPLA) is an efficacious adjuvant for inactivated rabies vaccines

C Chen, C Zhang, R Li, Z Wang, Y Yuan, H Li, Z Fu… - Viruses, 2019 - mdpi.com
Rabies, as one of the most threatening zoonoses in the world, causes a fatal central nervous
system (CNS) disease. So far, vaccination with rabies vaccines has been the most effective …

Lab-attenuated rabies virus facilitates opening of the blood-brain barrier by inducing matrix metallopeptidase 8

A Fang, Y Yuan, F Huang, C Wang, D Tian… - Journal of …, 2022 - Am Soc Microbiol
Infection with laboratory-attenuated rabies virus (RABV), but not wild-type (wt) RABV, can
enhance the permeability of the blood-brain barrier (BBB), which is considered a key …

Rabies vaccine: Recent update and comprehensive review of in vitro and in vivo studies

M Abedi, SM Haftcheshmeh, R Bashar… - Process …, 2023 - Elsevier
Rabies is a zoonotic and progressive viral disease in warm-blooded animals including
human that is almost always fatal following the onset of clinical symptoms. Increasing …

Construction and evaluation of recombinant Lactobacillus plantarum NC8 delivering one single or two copies of G protein fused with a DC-targeting peptide (DCpep) …

J Wang, H Jiang, R Yang, S Zhang, W Zhao, J Hu… - Veterinary …, 2020 - Elsevier
Rabies remains an important public health threat in most developing countries. To develop a
more effective and safe oral vaccine against rabies, we constructed recombinant …

The broad immunomodulatory effects of IL-7 and its application in vaccines

J Huang, Z Long, R Jia, M Wang, D Zhu, M Liu… - Frontiers in …, 2021 - frontiersin.org
Interleukin-7 (IL-7) is produced by stromal cells, keratinocytes, and epithelial cells in host
tissues or tumors and exerts a wide range of immune effects mediated by the IL-7 receptor …

In vitro IL-6/IL-6R Trans-Signaling in Fibroblasts Releases Cytokines That May Be Linked to the Pathogenesis of IgG4-Related Disease

J Zongfei, C Rongyi, C Xiaomeng, M Lili… - Frontiers in …, 2020 - frontiersin.org
Background: The remarkable mechanisms of storiform fibrosis and the formation of high
levels of IgG4 with a pathogenic germinal center (GC) in the inflammatory tissue of IgG4-RD …

A novel rabies vaccine based on infectious propagating particles derived from hybrid VEEV-Rabies replicon

YN Zhang, C Chen, CL Deng, C Zhang, N Li, Z Wang… - …, 2020 - thelancet.com
Abstract Background Live attenuated vaccines (LAVs) can mimic natural infection and have
advantages to stimulate a robust and sustained immune response as well as to confer long …