Although recent years have seen large decreases in the overall global rate of suicide
fatalities, this trend is not reflected everywhere. Suicide and suicidal behaviour continue to …

This narrative state-of-the-art review paper describes the progress in the understanding and
treatment of Posttraumatic Stress Disorder (PTSD). Over the last four decades, the scientific …

Major depressive disorder (MDD) has an enormous impact on global disease burden,
affecting millions of people worldwide and ranking as a leading cause of disability for almost …

Major depressive disorder (MDD) is a leading cause of disease burden worldwide. While the
incidence, symptoms and treatment of MDD all point toward major sex differences, the …

Randomized trials have shown that selective serotonin reuptake inhibitors (SSRIs) and
serotonin-norepinephrine reuptake inhibitors (SNRIs) have better safety profiles than …

BACKGROUND: Depression is the most common psychiatric disorder in people who die by
suicide. Awareness of risk factors for suicide in depression is important for clinicians …

BackgroundSuicide attempt (SA), which is one of the strongest predictors of completed
suicide, is common in major depressive disorder (MDD) but its prevalence across …

Suicidal behavior is a major problem worldwide and, at the same time, has received
relatively little empirical attention. This relative lack of empirical attention may be due in part …

Despite increasing evidence supporting the neuroinflammatory theory of depression, little is
known about cerebral macrophages in individuals suffering from major depression. In the …

Maternal care influences hypothalamic-pituitary-adrenal (HPA) function in the rat through
epigenetic programming of glucocorticoid receptor expression. In humans, childhood abuse …