Advanced analytical and informatic strategies for metabolite annotation in untargeted metabolomics

Y Cai, Z Zhou, ZJ Zhu - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Liquid chromatography–mass spectrometry (LC–MS)-based untargeted metabolomics is
constantly challenged by large-scale and unambiguous metabolite annotation in complex …

Embracing lipidomics at single-cell resolution: Promises and pitfalls

Z Wang, M Cao, SM Lam, G Shui - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Technological innovations have transformed the way scientists approach biological and
clinical questions, transiting from conventional ensemble assays in bulk to emphasize on the …

Collision cross section prediction based on machine learning

X Li, H Wang, M Jiang, M Ding, X Xu, B Xu, Y Zou, Y Yu… - Molecules, 2023 - mdpi.com
Ion mobility-mass spectrometry (IM-MS) is a powerful separation technique providing an
additional dimension of separation to support the enhanced separation and characterization …

Collision cross section measurement and prediction methods in omics

KY Kartowikromo, OE Olajide… - Journal of mass …, 2023 - Wiley Online Library
Omics studies such as metabolomics, lipidomics, and proteomics have become important for
understanding the mechanisms in living organisms. However, the compounds detected are …

Multiplatform untargeted metabolomics

MJ Jeppesen, R Powers - Magnetic Resonance in Chemistry, 2023 - Wiley Online Library
Metabolomics samples like human urine or serum contain upwards of a few thousand
metabolites, but individual analytical techniques can only characterize a few hundred …

Biological mass spectrometry enables spatiotemporal 'omics: From tissues to cells to organelles

LR Pade, KE Stepler, EP Portero… - Mass spectrometry …, 2024 - Wiley Online Library
Biological processes unfold across broad spatial and temporal dimensions, and
measurement of the underlying molecular world is essential to their understanding …

A re-calibration procedure for interoperable lipid collision cross section values measured by traveling wave ion mobility spectrometry

AC George, I Schmitz-Afonso, V Marie, B Colsch… - Analytica Chimica …, 2022 - Elsevier
Collision cross sections (CCS) have been described as relevant molecular descriptors in
metabolomics and lipidomics analyses for ascertaining compound identity. Ion mobility …

Lipidomic Comparisons of Whole Cream Buttermilk Whey and Cheese Whey Cream Buttermilk of Caprine Milk

B Song, D Liu, J Lu, X Tao, X Peng, T Wu… - Journal of Agricultural …, 2024 - ACS Publications
Buttermilk is a potential material for the production of a milk fat globule membrane (MFGM)
and can be mainly classified into two types: whole cream buttermilk and cheese whey cream …

[HTML][HTML] Hyphenation of Supercritical Fluid Chromatography and Trapped Ion Mobility-Mass Spectrometry for Quantitative Lipidomics

J Scholz, E Rudt, A Gremme, CM Gaßmöller… - Analytica Chimica …, 2024 - Elsevier
Background Lipidomics studies require rapid separations with accurate and reliable
quantification results to further elucidate the role of lipids in biological processes and their …

[HTML][HTML] Simultaneous Multi-Omics Analysis by Direct Infusion Mass Spectrometry (SMAD-MS)

Y Jiang, I Salladay-Perez, A Momenzadeh… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Combined multi-omics analysis of proteomics, polar metabolomics, and lipidomics requires
separate liquid chromatography–mass spectrometry (LC–MS) platforms for each omics …