The study of hepatic fibrosis, or scarring in response to chronic liver injury, has witnessed
tremendous progress in the past two decades. Clarification of the cellular sources of scar …

Liver fibrosis is caused by many chronic diseases. Liver injury results in activation of
collagen‐producing cells and excessive deposition of extracellular matrix proteins. This …

Many types of bioactive peptides that inhibit angiotensin I, angiotensin I converting enzyme
(ACE) and Ang II type 1 receptor (AT1) in the cardiovascular system contribute to the …

BACKGROUND The epidemiologic and clinical characteristics of heart transplant (HTx)
recipients during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Rationale Hypertension, obesity and diabetes are major risk factors associated with
morbidities underlying COVID-19 infections. Regression analysis correlated presence of …

Significance: Despite recent medical advances, cardiovascular disease and heart failure
(HF) continue to be major health concerns, and related mortality remains high. As a result …

More than a century after its discovery, the physiological implications of the renin–
angiotensin system (RAS) continue to expand, with the identification of new components …

The activation of the conventional renin angiotensin aldosterone system (RAAS) plays a
seminal role on the physiologic regulation of blood volume and blood pressure and it is …

BACKGROUND: In chronic heart failure (CHF), persistent autonomic derangement and
neurohumoral activation cause structural end-organ damage, decrease exercise capacity …

Background Given the sparse data on the renin-angiotensin system (RAS) and its biological
effector molecules ACE1 and ACE2 in pediatric COVID-19 cases, we investigated whether …