Towards a unified mechanistic theory of aging

G Barja - Experimental gerontology, 2019 - Elsevier
A large amount of the longevity-modulating genes discovered during the last two decades
are highly conserved during evolution from yeast and invertebrates to mammals. Many …

Particle swarm optimization with an aging leader and challengers

WN Chen, J Zhang, Y Lin, N Chen… - IEEE transactions on …, 2012 - ieeexplore.ieee.org
In nature, almost every organism ages and has a limited lifespan. Aging has been explored
by biologists to be an important mechanism for maintaining diversity. In a social animal …

[HTML][HTML] Whole organism aging: Parabiosis, inflammaging, epigenetics, and peripheral and central aging clocks. The ARS of aging

R Pamplona, M Jové, J Gómez, G Barja - Experimental Gerontology, 2023 - Elsevier
The strong interest shown in the study of the causes of aging in recent decades has
uncovered many mechanisms that could contribute to the rate of aging. These include …

Distributed individuals for multiple peaks: A novel differential evolution for multimodal optimization problems

ZG Chen, ZH Zhan, H Wang… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
Locating more peaks and refining the solution accuracy on the found peaks are two
challenging issues in solving multimodal optimization problems (MMOPs). To deal with …

A hybrid whale optimization algorithm based on modified differential evolution for global optimization problems

J Luo, B Shi - Applied Intelligence, 2019 - Springer
Whale optimization algorithm (WOA) is a biological-inspired optimization algorithm with the
advantage of global optimization ability, less control parameters and easy implementation. It …

A shuffled multi-swarm micro-migrating birds optimizer for a multi-resource-constrained flexible job shop scheduling problem

L Gao, QK Pan - Information Sciences, 2016 - Elsevier
Scheduling problems with resource constraints have been a new research trend in recent
years. This paper addresses a multi-resource-constrained flexible job shop scheduling …

A hybrid memory-based dragonfly algorithm with differential evolution for engineering application

S Debnath, S Baishya, D Sen, W Arif - Engineering with Computers, 2021 - Springer
The dragonfly algorithm (DA) is a swarm-based stochastic algorithm which possesses static
and dynamic behavior of swarm and is gaining meaningful popularity due to its low …

Programmed life span in the context of evolvability

J Mitteldorf, ACR Martins - The American Naturalist, 2014 - journals.uchicago.edu
Population turnover is necessary for progressive evolution. In the context of a niche with
fixed carrying capacity, aging contributes to the rate of population turnover. Theoretically, a …

Aging, evolvability, and the individual benefit requirement; medical implications of aging theory controversies

TC Goldsmith - Journal of theoretical biology, 2008 - Elsevier
There is a class of theories of aging (variously termed adaptive aging, aging by design,
aging selected for its own sake, or programmed death theories) that hold that an organism …

Fetal origins—A life cycle model of health and aging from conception to death

CJ Dalgaard, CW Hansen, H Strulik - Health Economics, 2021 - Wiley Online Library
The fetal origins hypothesis suggests that health and nutrition shocks in utero are causally
related to health deficits in old age. It has received considerable empirical support, both …