Autoimmune diseases recognize a multifactorial pathogenesis, although the exact
mechanism responsible for their onset remains to be fully elucidated. Over the past few …

Natural killer (NK) cells are innate lymphocytes that play a critical role in early host defense
against viruses. Through their cytolytic capacity and generation of cytokines and …

Immune related abnormalities have repeatedly been reported in autism spectrum disorders
(ASD), including evidence of immune dysregulation and autoimmune phenomena. NK cells …

Natural killer (NK) cells have been implicated in tumour surveillance and in the early control
of several microbial infections. In autoimmune disease their involvement in these processes …

Natural killer (NK) cells are fast-acting and versatile lymphocytes that are critical effectors of
innate immunity, adaptive immunity, and placental development. Controlling NK cell function …

As major components of innate immunity, NK cells not only exert cell-mediated cytotoxicity
against tumor cells or infected cells, but also act to regulate the function of other immune …

Killer cell immunoglobulin‐like receptors (KIRs) have a central role in the control of natural
killer (NK) cell function. The functions of the activating KIRs, as compared to those of the …

Interactions between killer immunoglobulin-like receptors (KIRs) and their HLA-A,-B, and-C
ligands diversify the functions of human natural killer cells. Consequently, combinations of …

Systemic sclerosis (SSc) is an autoinflammatory, fibrotic condition of unknown aetiology. The
presence of detectable autoantibodies against diverse nuclear antigens, as well as strong …

Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by a
breakdown of self-tolerance in B cells and the production of antibodies against nuclear self …