Carbapenem-resistant Enterobacteriaceae (CRE) are a major global public health concern
and pose a serious threat to immunocompromised hosts, particularly patients with …

The prevalence of carbapenem-resistant gram-negative bacterial pathogens (CRGNs) has
increased dramatically during the last 10 years, but the optimal treatment for CRGN …

Carbapenem-resistant Enterobacteriaceae (CRE) are emerging global pathogens. The
spread of CRE to transplant recipients and patients with hematologic malignancies has …

These updated guidelines from the Infectious Diseases Community of Practice of the
American Society of Transplantation review the diagnosis, prevention, and management of …

Polymyxin B and colistin (polymyxin E) are bactericidal pentacationic lipopeptides that act
specifically on Gram-negative bacteria, first by disrupting their outermost permeability …

The recently developed SUPERCARBA medium was evaluated together with 2
commercially available selective culture media containing carbapenems: CHROMagar KPC …

Since the discovery of penicillin 80 years ago, gram‐negative bacteria have become
proficient at evading the lethal activity of β‐lactam antibiotics, principally through the …

Carbapenemase-producing isolates of the Enterobacteriaceae are reported increasingly
worldwide (9). Besides the emergence of OXA-48 and NDM-1 producers in specific …

Polymyxins are naturally occurring cyclic lipopeptides that were discovered more than 60
years ago. They have a narrow antibacterial spectrum, which is mainly against Gram …

Objectives The objective of this study was to study the contribution of the multidrug
resistance AcrAB-TolC efflux system to carbapenem resistance in carbapenemase …