Calcium ions are ubiquitous intracellular messengers. An increase in the cytosolic Ca2+
concentration activates many proteins, including calmodulin and the Ca2+/calmodulin …

Calcineurin signaling plays diverse roles in fungi in regulating stress responses,
morphogenesis and pathogenesis. Although calcineurin signaling is conserved among …

Many pathogenic fungi are dimorphic and switch between yeast and filamentous states. This
switch alters host-microbe interactions and is critical for pathogenicity. However, in …

Calcineurin plays essential roles in virulence and growth of pathogenic fungi and is a target
of the natural products FK 506 and C yclosporine A. In the pathogenic mucoralean fungus M …

The fungal kingdom is vast, spanning∼ 1.5 to as many as 5 million species diverse as
unicellular yeasts, filamentous fungi, mushrooms, lichens, and both plant and animal …

In recent years, we have seen an increase in the number of immunocompromised cohorts as
a result of infections and/or medical conditions, which has resulted in an increased …

The heat shock proteins (Hsps) act as a molecular chaperone to stabilize client proteins
involved in various cell functions in fungi. Hsps are classified into different families such as …

Candida glabrata is an emerging human fungal pathogen that is frequently drug tolerant,
resulting in difficulties in treatment and a higher mortality in immunocompromised patients …

Candida dubliniensis is an emerging pathogenic yeast species closely related to Candida
albicans and frequently found colonizing or infecting the oral cavities of HIV/AIDS patients …

Invasive fungal infections (IFIs) are emerging as a serious threat to public health and are
associated with high incidence and mortality. IFIs also represent a frequent complication in …