Precision treatment in advanced hepatocellular carcinoma

X Yang, C Yang, S Zhang, H Geng, AX Zhu… - Cancer Cell, 2024 - cell.com
The past decade has witnessed significant advances in the systemic treatment of advanced
hepatocellular carcinoma (HCC). Nevertheless, the newly developed treatment strategies …

Liver biopsy for assessment of chronic liver diseases: a synopsis

AB Chowdhury, KJ Mehta - Clinical and experimental medicine, 2023 - Springer
The world-wide increase in chronic liver disease (CLD) calls for refinement of diagnostic and
prognostic measures for early and accurate disease detection and management …

CIRSE standards of practice on hepatic transarterial chemoembolisation

P Lucatelli, M Burrel, B Guiu, G de Rubeis… - Cardiovascular and …, 2021 - Springer
Abstract This CIRSE Standards of Practice document is aimed at interventional radiologists
and provides best practices for performing transarterial chemoembolisation. It has been …

Deep learning-based classification of hepatocellular nodular lesions on whole-slide histopathologic images

N Cheng, Y Ren, J Zhou, Y Zhang, D Wang, X Zhang… - Gastroenterology, 2022 - Elsevier
Background & Aims Hepatocellular nodular lesions (HNLs) constitute a heterogeneous
group of disorders. Differential diagnosis among these lesions, especially high-grade …

[HTML][HTML] High serum IL-6 correlates with reduced clinical benefit of atezolizumab and bevacizumab in unresectable hepatocellular carcinoma

H Yang, B Kang, Y Ha, SH Lee, I Kim, H Kim, WS Lee… - JHEP Reports, 2023 - Elsevier
Background & Aims We elucidated the clinical and immunologic implications of serum IL-6
levels in patients with unresectable hepatocellular carcinoma (HCC) treated with …

Biomarkers for hepatocellular carcinoma: from origin to clinical diagnosis

MA Omar, MM Omran, K Farid, AA Tabll, YE Shahein… - Biomedicines, 2023 - mdpi.com
The incidence of hepatocellular carcinoma (HCC) and HCC-related deaths has increased
over the last few decades. There are several risk factors of HCC such as viral hepatitis (B …

Overdiagnosis of hepatocellular carcinoma: prevented by guidelines?

NE Rich, AG Singal - Hepatology, 2022 - Wiley Online Library
Overdiagnosis refers to detection of disease that would not otherwise become clinically
apparent during a patient's lifetime. Overdiagnosis is common and has been reported for …

Gene expression signature as a surrogate marker of microvascular invasion on routine hepatocellular carcinoma biopsies

A Beaufrère, S Caruso, J Calderaro, N Poté, JC Bijot… - Journal of …, 2022 - Elsevier
Background & Aims Microvascular invasion (MVI), a major risk factor for tumor recurrence
after surgery in hepatocellular carcinoma (HCC), is only detectable by microscopic …

[HTML][HTML] Single-cell immune signature for detecting early-stage HCC and early assessing anti-PD-1 immunotherapy efficacy

J Shi, J Liu, X Tu, B Li, Z Tong, T Wang… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background The early diagnosis of hepatocellular carcinoma (HCC) can greatly improve
patients'5-year survival rate, and the early efficacy assessment is important for oncologists to …

Activity-based photoacoustic probe for biopsy-free assessment of copper in murine models of Wilson's disease and liver metastasis

MY Lucero, Y Tang, CJ Zhang, S Su… - Proceedings of the …, 2021 - National Acad Sciences
The development of high-performance photoacoustic (PA) probes that can monitor disease
biomarkers in deep tissue has the potential to replace invasive medical procedures such as …