Neutrophils have always been considered as uncomplicated front-line troopers of the innate
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …

Leukocyte migration through activated venular walls is a fundamental immune response that
is prerequisite to the entry of effector cells such as neutrophils, monocytes, and effector T …

Neutrophils have traditionally been thought of as simple foot soldiers of the innate immune
system with a restricted set of pro-inflammatory functions. More recently, it has become …

Monocytes fundamentally contribute to immune surveillance and the inflammatory response
in immunoinflammatory diseases like atherosclerosis. Recruitment of these cells to the site …

Neutrophils are the primary cells recruited to inflamed sites during an innate immune
response to tissue damage and/or infection. They are finely sensitive to inciting stimuli to …

Neutrophils are produced in the bone marrow from stem cells that proliferate and
differentiate to mature neutrophils fully equipped with an armory of granules. These contain …

Neutrophils represent the first line of cellular defense against invading microorganism by
rapidly moving across the blood–endothelial cell (EC) barrier and exerting effector cell …

Here we focus on how neutrophils have a key regulatory role in vascular inflammation.
Recent studies using advanced imaging techniques have yielded new insights into the …

Cell motility is central to tissue homeostasis in health and disease, and there is hardly any
cell in the body that is not motile at a given point in its life cycle. Important physiological …

The shuttling of leukocytes between the bloodstream and interstitial tissues involves different
locomotion strategies that are governed by locally presented soluble and cell-bound signals …