ASACO: Automatic and Serial Analysis of CO-expression to discover gene modifiers with potential use in drug repurposing

C Moral-Turón, G Asencio-Cortés… - Briefings in …, 2024 - academic.oup.com
Massive gene expression analyses are widely used to find differentially expressed genes
under specific conditions. The results of these experiments are often available in public …

Biostatistical Aspects of Whole Genome Sequencing Studies: Preprocessing and Quality Control

RO Betschart, C Riccio, D Aguilera‐Garcia… - Biometrical …, 2024 - Wiley Online Library
Rapid advances in high‐throughput DNA sequencing technologies have enabled large‐
scale whole genome sequencing (WGS) studies. Before performing association analysis …

Integrating rare pathogenic variant prioritization with gene‐based association analysis to identify novel genes and relevant multimodal traits for Alzheimer's disease

J Cao, C Zhang, CYZ Lo, Q Guo, J Ding… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Increasing evidence has highlighted rare variants in Alzheimer's disease
(AD). However, insufficient sample sizes, especially in underrepresented ethnic groups …

Towards Rigorous Diagnostics for Vaccine Injury

M Halma - 2023 - preprints.org
Delineating the epidemic of vaccine injury from the coterminous condition long covid is a
challenging prospect, but one with many implications not just for treatment, but also has …