Emerging biopharmaceuticals from bioactive peptides derived from marine organisms

K Anjum, SQ Abbas, N Akhter… - Chemical biology & …, 2017 - Wiley Online Library
Biologically active natural products are spontaneous medicinal entrants, which encourage
synthetic access for enhancing and supporting drug discovery and development. Marine …

Challenges and rewards of research in marine natural products chemistry in Brazil

RGS Berlinck, E Hajdu, RM da Rocha… - Journal of Natural …, 2004 - ACS Publications
Brazil is blessed with a great biodiversity, which constitutes one of the most important
sources of biologically active compounds, even if it has been largely underexplored. As is …

The cytotoxic and embryotoxic effects of kaurenoic acid, a diterpene isolated from Copaifera langsdorffii oleo-resin

LV Costa-Lotufo, GMA Cunha, PAM Farias, GSB Viana… - Toxicon, 2002 - Elsevier
In this work, we studied the effects of kaurenoic acid, a diterpene isolated from the oleo-resin
of Copaifera langsdorffii in developing sea urchin (Lytechinus variegatus) embryos, on …

Antimicrobial activity of the reef sponge Amphimedon viridis from the Red Sea: evidence for selective toxicity

D Kelman, Y Kashman, E Rosenberg, M Ilan… - Aquatic Microbial …, 2001 - int-res.com
Living benthic marine organisms such as sponges and corals are frequently colonized by
bacteria that may be pathogenic to them. One of the means by which they are able to combat …

Antiangiogenic and antitumoral properties of a polysaccharide isolated from the seaweed Sargassum stenophyllum

PF Dias, JM Siqueira, LF Vendruscolo, TJ Neiva… - Cancer Chemotherapy …, 2005 - Springer
The potential antiangiogenic and antitumoral properties of SargA, a polysaccharide
extracted from the brown marine alga Sargassum stenophyllum, were studied in assays …

[PDF][PDF] Anticancer activity of Sargassum oligocystum water extract against human cancer cell lines

K Zandi, S Ahmadzadeh, S Tajbakhsh… - European review for …, 2010 - academia.edu
Materials and Methods: The research was performed as an in vitro study. The effect of the
alga extract on proliferation of cell lines were measured by two methods: MTT assay and …

Effects of Caribbean sponge extracts on bacterial attachment

SR Kelly, PR Jensen, TP Henkel, W Fenical… - Aquatic Microbial …, 2003 - int-res.com
Attachment is one of the first steps in bacterial colonization. By inhibiting bacterial
attachment on surface cells, sponges may not only prevent infection, but also the process of …

In vitro antitumor activity of Gracilaria corticata (a red alga) against Jurkat and molt-4 human cancer cell lines

K Zandi, S Tajbakhsh, I Nabipour, Z Rastian… - African Journal of …, 2010 - ajol.info
Gracilaria corticata is a red alga which can be collected from many sea coasts around the
world such as China, India, Persian Gulf, etc. The Persian Gulf is a unique marine habitat …

[HTML][HTML] Cytotoxic profile of natural and some modified bufadienolides from toad Rhinella schneideri parotoid gland secretion

GA Cunha-Filho, IS Resck, BC Cavalcanti, CÓ Pessoa… - Toxicon, 2010 - Elsevier
Cutaneous secretions of toad species are an important source of bufadienolides,
compounds that exhibit interesting structural features and biopharmacological properties …

[HTML][HTML] Rho family of ras-like GTPases in early-branching animals

S Beljan, M Herak Bosnar, H Ćetković - Cells, 2020 - mdpi.com
Non-bilaterian animals consist of four phyla; Porifera, Cnidaria, Ctenophora, and Placozoa.
These early-diverging animals are crucial for understanding the evolution of the entire …