Laminin-111-Enriched fibrin hydrogels enhance functional muscle regeneration following trauma

N Ziemkiewicz, GM Hilliard, AJ Dunn… - … Engineering Part A, 2022 - liebertpub.com
Volumetric muscle loss (VML) is the surgical or traumatic loss of skeletal muscle, which can
cause loss of limb function or permanent disability. VML injuries overwhelms the …

Laminin-111 enriched fibrin hydrogels for skeletal muscle regeneration

M Marcinczyk, H Elmashhady, M Talovic, A Dunn… - Biomaterials, 2017 - Elsevier
Abstract Laminin (LM)-111 supplementation has improved muscle regeneration in several
models of disease and injury. This study investigated a novel hydrogel composed of …

Optimizing fibrin hydrogel toward effective neural progenitor cell delivery in spinal cord injury

T Sudhadevi, HS Vijayakumar, EV Hariharan… - Biomedical …, 2021 - iopscience.iop.org
Transplantation of neural progenitor cell (NPC) possessing the potential to differentiate into
neurons may guard against spinal cord injury (SCI)-associated neuronal trauma. We …

Neural Tissue Engineering with Rat Adipose-Derived Mesenchymal Stem Cells: The Role of an Injectable, Resorbable Hydrogel Scaffold Derived from Oxidized …

T Sudhadevi, R Resmi, K Chandrababu… - ACS Applied Bio …, 2023 - ACS Publications
The central nervous system has limited regeneration potential. The multipotency of adipose-
derived mesenchymal stem cells (ADMSC) makes them an ideal autologous cell source for …

Unravelling the Parkinson's puzzle, from medications and surgery to stem cells and genes: a comprehensive review of current and future management strategies

K Chandrababu, V Radhakrishnan, AS Anjana… - Experimental Brain …, 2024 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder, prevalent in the elderly
population. Neuropathological hallmarks of PD include loss of dopaminergic cells in the …

Isolation and Culture of Pig Spermatogonial Stem Cells and Their in Vitro Differentiation into Neuron-Like Cells and Adipocytes

X Wang, T Chen, Y Zhang, B Li, Q Xu… - International journal of …, 2015 - mdpi.com
Spermatogonial stem cells (SSCs) renew themselves throughout the life of an organism and
also differentiate into sperm in the adult. They are multipopent and therefore, can be induced …

Exploitation of fibrin-based signaling niche for deriving progenitors from human adipose-derived mesenchymal stem cells towards potential neural engineering …

K Chandrababu, M Senan, LK Krishnan - Scientific Reports, 2020 - nature.com
Adipose-derived mesenchymal stem cells (hADMSC) retaining proliferation and multi-
differentiation potential may support the central nervous system (CNS) regeneration …

Differentiation of circulating neural progenitor cells in vitro on fibrin-based composite-matrix involves Wnt-β-catenin-like signaling

S Tara, LK Krishnan - Journal of cell communication and signaling, 2019 - Springer
Isolation of progenitors with regenerative potential and their in vitro induction to specific
lineage may be necessary for effective cell transplantation outcome. Earlier, we …

Adult human peripheral blood mononuclear cells are capable of producing neurocyte or photoreceptor-like cells that survive in mouse eyes after preinduction with …

B Xian, Y Zhang, Y Peng, J Huang, W Li… - Stem cells …, 2016 - academic.oup.com
Adult human peripheral blood mononuclear cells (hPBMCs) exhibit pluripotency in vitro and
so may be a valuable cell source for regenerative therapies. The efficacy of such therapies …

[PDF][PDF] Efficient generation of tyrosine hydroxylase-expressing dopamine-producing neurons from rat peripheral blood progenitors using a combination of growth …

P Prakash, R Rajan, A Deepti, A Vengellur… - Archives of Clinical …, 2023 - fortuneonline.org
Parkinson's disease (PD) is a neurodegenerative disorder that affects dopaminergic
neurons of the substantia nigra, with a prevalence of 1 in 500 individuals. Current …