Antimicrobial peptides in 2014

G Wang, B Mishra, K Lau, T Lushnikova, R Golla… - Pharmaceuticals, 2015 - mdpi.com
This article highlights new members, novel mechanisms of action, new functions, and
interesting applications of antimicrobial peptides reported in 2014. As of December 2014 …

Scientific Opinion on the state of the science on pesticide risk assessment for amphibians and reptiles

EFSA Panel on Plant Protection Products and … - Efsa …, 2018 - Wiley Online Library
Following a request from EFSA, the Panel on Plant Protection Products and their Residues
developed an opinion on the science to support the potential development of a risk …

Machine learning-guided discovery and design of non-hemolytic peptides

F Plisson, O Ramírez-Sánchez… - Scientific reports, 2020 - nature.com
Reducing hurdles to clinical trials without compromising the therapeutic promises of peptide
candidates becomes an essential step in peptide-based drug design. Machine-learning …

Community structure and function of amphibian skin microbes: an experiment with bullfrogs exposed to a chytrid fungus

JB Walke, MH Becker, SC Loftus, LL House… - PloS one, 2015 - journals.plos.org
The vertebrate microbiome contributes to disease resistance, but few experiments have
examined the link between microbiome community structure and disease resistance …

Temporins: an approach of potential pharmaceutic candidates

SM Romero, AB Cardillo, MC Martínez Ceron… - Surgical …, 2020 - liebertpub.com
Antimicrobial peptides (AMPs), also known as host defense peptides, are small and mostly
polycationic molecules that form part of the innate immune response. There are currently …

Antibacterial activity affected by the conformational flexibility in glycine–lysine based α-helical antimicrobial peptides

T Rončević, D Vukičević, N Ilić, L Krce… - Journal of medicinal …, 2018 - ACS Publications
Antimicrobial peptides often show broad-spectrum activity due to a mechanism based on
bacterial membrane disruption, which also reduces development of permanent resistance, a …

Peptidomic comparison and characterization of the major components of the venom of the giant ant Dinoponera quadriceps collected in four different areas of Brazil

CT Cologna, J dos Santos Cardoso, E Jourdan… - Journal of …, 2013 - Elsevier
Despite the noxious effects inflicted by Dinoponera ant's envenomation, the information
about the biological properties and composition of their venom is still very limited. Ants from …

Alkaloid-based chemical defenses and diet in six species of Australian poison frogs in the genus Pseudophryne (Myobatrachidae)

M Sague, V Dudaitis, L Plumert, KDL Umbers… - Evolutionary …, 2023 - Springer
Poison frogs are well known for their ability to sequester alkaloids from their diet of leaf-litter
arthropods for use in defense against predators and pathogens. Australian frogs in the …

Antimicrobial Peptides from Skin Secretions of Hypsiboas pulchellus (Anura: Hylidae)

A Siano, MV Húmpola, E de Oliveira… - Journal of Natural …, 2014 - ACS Publications
The skin of many amphibians produces a large repertoire of antimicrobial peptides that are
crucial in the first line of defense against microbial invasion. Despite the immense richness …

Esculentin-2CHa: a host-defense peptide with differential cytotoxicity against bacteria, erythrocytes and tumor cells

S Attoub, M Mechkarska, A Sonnevend… - Peptides, 2013 - Elsevier
The host-defense peptide, esculentin-2CHa (GFSSIFRGVA10KFASKGLGK
D20LAKLGVDLVA30 CKISKQC) shows potent (MIC≤ 6μM) growth inhibitory activity against …