Significance: Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique to
distinguish the unique molecular environment of fluorophores. FLIM measures the time a …

When a molecule absorbs a photon of appropriate energy, a chain of photophysical events
ensues, such as internal conversion or vibrational relaxation (loss of energy in the absence …

As a well-known medical imaging methodology, intravascular ultrasound (IVUS) imaging
plays a critical role in diagnosis, treatment guidance and post-treatment assessment of …

Cumulative evidence from histology-based studies demonstrate that the currently available
intravascular imaging techniques have fundamental limitations that do not allow complete …

This article presents an overview of time-resolved (lifetime) fluorescence techniques used in
biomedical diagnostics. In particular, we review the development of time-resolved …

Atherosclerosis is a major cause of mortality and morbidity, which is mainly driven by
complications such as myocardial infarction and stroke. These complications are caused by …

When light is incident to a biological tissue surface, combinations of optical processes occur,
such as reflection, absorption, elastic and non-elastic scattering, and fluorescence. Analysis …

There is an ever-increasing demand for new imaging methods that can provide additional
information about the coronary wall to better characterize and stratify high-risk plaques, and …

Objectives: This study hypothesized that bright spots in intravascular optical coherence
tomography (IVOCT) images may originate by colocalization of plaque materials of differing …

Backgrounds: Omentin-1 is a novel cytokine that is primarily released by the epicardial
adipose tissue. Molecular structure analysis revealed that it contained a fibrinogen-like …