The impact of comorbidity on cancer survival: a review

M Søgaard, RW Thomsen, KS Bossen… - Clinical …, 2013 - Taylor & Francis
Background A number of studies have shown poorer survival among cancer patients with
comorbidity. Several mechanisms may underlie this finding. In this review we summarize the …

Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials

AM Algra, PM Rothwell - The lancet oncology, 2012 - thelancet.com
Background Long-term follow-up of randomised trials of aspirin in prevention of vascular
events showed that daily aspirin reduced the incidence of colorectal cancer and several …

Aspirin intake and survival after breast cancer

MD Holmes, WY Chen, L Li, E Hertzmark… - Journal of clinical …, 2010 - ascopubs.org
Purpose Animal and in vitro studies suggest that aspirin may inhibit breast cancer
metastasis. We studied whether aspirin use among women with breast cancer decreased …

[HTML][HTML] Cyclooxygenase-2 and the inflammogenesis of breast cancer

RE Harris, BC Casto, ZM Harris - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
Cohesive scientific evidence from molecular, animal, and human investigations supports the
hypothesis that constitutive overexpression of cyclooxygenase-2 (COX-2) is a ubiquitous …

Cyclooxygenases, prostanoids, and tumor progression

MT Wang, KV Honn, D Nie - Cancer and Metastasis Reviews, 2007 - Springer
In response to various growth factors, hormones or cytokines, arachidonic acid can be
mobilized from phospholipids pools and converted to bioactive eicosanoids through …

[HTML][HTML] Aspirin in the treatment of cancer: reductions in metastatic spread and in mortality: a systematic review and meta-analyses of published studies

PC Elwood, G Morgan, JE Pickering, J Galante… - PloS one, 2016 - journals.plos.org
Background Low-dose aspirin has been shown to reduce the incidence of cancer, but its
role in the treatment of cancer is uncertain. Objectives We conducted a systematic search of …

Nuclear factor-κB in development, prevention, and therapy of cancer

C Van Waes - Clinical cancer research, 2007 - AACR
Nuclear factor-κB (NF-κB) is a signal transcription factor that has emerged as an important
modulator of altered gene programs and malignant phenotype in development of cancer …

Breast cancer survival among young women: a review of the role of modifiable lifestyle factors

DR Brenner, NT Brockton, J Kotsopoulos… - Cancer causes & …, 2016 - Springer
Almost 7% of breast cancers are diagnosed among women age 40 years and younger in
Western populations. Clinical outcomes among young women are worse. Early age-of-onset …

Threats to validity of nonrandomized studies of postdiagnosis exposures on cancer recurrence and survival

J Chubak, DM Boudreau, HS Wirtz… - Journal of the …, 2013 - academic.oup.com
Studies of the effects of exposures after cancer diagnosis on cancer recurrence and survival
can provide important information to the growing group of cancer survivors. Observational …

Aspirin use and survival after the diagnosis of breast cancer: a population-based cohort study

DM Fraser, FM Sullivan, AM Thompson… - British journal of …, 2014 - nature.com
Background: Aspirin use has been associated with a reduced cancer incidence and fewer
deaths from cancer. This study examined whether women with breast cancer prescribed …