[HTML][HTML] Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

[HTML][HTML] Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021 - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

A manual for the glasgow outcome scale-extended interview

L Wilson, K Boase, LD Nelson, NR Temkin… - Journal of …, 2021 - liebertpub.com
The Glasgow Outcome Scale-Extended (GOSE) has become one of the most widely used
outcome instruments to assess global disability and recovery after traumatic brain injury …

Functional outcomes over the first year after moderate to severe traumatic brain injury in the prospective, longitudinal TRACK-TBI study

MA McCrea, JT Giacino, J Barber, NR Temkin… - JAMA …, 2021 - jamanetwork.com
Importance Moderate to severe traumatic brain injury (msTBI) is a major cause of death and
disability in the US and worldwide. Few studies have enabled prospective, longitudinal …

[HTML][HTML] Pathophysiology and treatment of cerebral edema in traumatic brain injury

RM Jha, PM Kochanek, JM Simard - Neuropharmacology, 2019 - Elsevier
Cerebral edema (CE) and resultant intracranial hypertension are associated with
unfavorable prognosis in traumatic brain injury (TBI). CE is a leading cause of in-hospital …

Recovery after mild traumatic brain injury in patients presenting to US level I trauma centers: a transforming research and clinical knowledge in traumatic brain injury …

LD Nelson, NR Temkin, S Dikmen, J Barber… - JAMA …, 2019 - jamanetwork.com
Importance Most traumatic brain injuries (TBIs) are classified as mild (mTBI) based on
admission Glasgow Coma Scale (GCS) scores of 13 to 15. The prevalence of persistent …

Prognostic value of day-of-injury plasma GFAP and UCH-L1 concentrations for predicting functional recovery after traumatic brain injury in patients from the US …

FK Korley, S Jain, X Sun, AM Puccio, JK Yue… - The Lancet …, 2022 - thelancet.com
Background The prognostic value of glial fibrillary acidic protein (GFAP) and ubiquitin C-
terminal hydrolase L1 (UCH-L1) as day-of-injury predictors of functional outcome after …

The Glasgow Coma Scale at 40 years: standing the test of time

G Teasdale, A Maas, F Lecky, G Manley… - The Lancet …, 2014 - thelancet.com
Summary Since 1974, the Glasgow Coma Scale has provided a practical method for
bedside assessment of impairment of conscious level, the clinical hallmark of acute brain …

[HTML][HTML] Global neurotrauma research challenges and opportunities

AM Rubiano, N Carney, R Chesnut, JC Puyana - Nature, 2015 - nature.com
Traumatic injury to the brain or spinal cord is one of the most serious public health problems
worldwide. The devastating impact of'trauma', a term used to define the global burden of …

Association between plasma GFAP concentrations and MRI abnormalities in patients with CT-negative traumatic brain injury in the TRACK-TBI cohort: a prospective …

JK Yue, EL Yuh, FK Korley, EA Winkler, X Sun… - The Lancet …, 2019 - thelancet.com
Background After traumatic brain injury (TBI), plasma concentration of glial fibrillary acidic
protein (GFAP) correlates with intracranial injury visible on CT scan. Some patients with …