Recent progress on the versatility of virus-like particles

C Qian, X Liu, Q Xu, Z Wang, J Chen, T Li, Q Zheng… - Vaccines, 2020 - mdpi.com
Virus-like particles (VLPs) are multimeric nanostructures composed of one or more structural
proteins of a virus in the absence of genetic material. Having similar morphology to natural …

Nanoparticle-based adjuvants and delivery systems for modern vaccines

B Filipić, I Pantelić, I Nikolić, D Majhen… - Vaccines, 2023 - mdpi.com
Ever since the development of the first vaccine, vaccination has had the great impact on
global health, leading to the decrease in the burden of numerous infectious diseases …

A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus

J Hobson-Peters, JJ Harrison, D Watterson… - Science translational …, 2019 - science.org
Flaviviruses such as dengue, yellow fever, Zika, West Nile, and Japanese encephalitis virus
present substantial global health burdens. New vaccines are being sought to address safety …

A role for Biofoundries in rapid development and validation of automated SARS-CoV-2 clinical diagnostics

MA Crone, M Priestman, M Ciechonska… - Nature …, 2020 - nature.com
The SARS-CoV-2 pandemic has shown how a rapid rise in demand for patient and
community sample testing can quickly overwhelm testing capability globally. With most …

COVID-19 vaccine platforms: Delivering on a promise?

M Verdecia, JF Kokai-Kun, M Kibbey… - Human vaccines & …, 2021 - Taylor & Francis
The emergence of the novel SARS-CoV-2 and COVID-19 has brought into sharp focus the
need for a vaccine to prevent this disease. Vaccines have saved millions of lives since their …

Plant‐made dengue virus‐like particles produced by co‐expression of structural and non‐structural proteins induce a humoral immune response in mice

D Ponndorf, Y Meshcheriakova… - Plant Biotechnology …, 2021 - Wiley Online Library
Dengue virus (DENV) is an emerging threat causing an estimated 390 million infections per
year. Dengvaxia, the only licensed vaccine, may not be adequately safe in young and …

A dengue virus serotype 1 mRNA-LNP vaccine elicits protective immune responses

CJ Wollner, M Richner, MA Hassert, AK Pinto… - Journal of …, 2021 - Am Soc Microbiol
Dengue virus (DENV) is the most common vector-borne viral disease, with nearly 400
million worldwide infections each year concentrated in the tropical and subtropical regions …

Nanosensors based on LSPR are able to serologically differentiate dengue from Zika infections

AF Versiani, EMN Martins, LM Andrade, L Cox… - Scientific reports, 2020 - nature.com
The Flaviviridae virus family was named after the Yellow-fever virus, and the latin term flavi
means “of golden color”. Dengue, caused by Dengue virus (DENV), is one of the most …

A chimeric dengue virus vaccine candidate delivered by high density microarray patches protects against infection in mice

JJY Choo, LJ Vet, CLD McMillan, JJ Harrison… - npj Vaccines, 2021 - nature.com
Dengue viruses (DENV) cause an estimated 390 million infections globally. With no dengue-
specific therapeutic treatment currently available, vaccination is the most promising strategy …

Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality

S Maciejewski, TJ Ruckwardt, KM Morabito… - Science translational …, 2020 - science.org
The emergence of Zika virus (ZIKV) in the Americas stimulated the development of multiple
ZIKV vaccine candidates. We previously developed two related DNA vaccine candidates …