APE1 is an essential endodeoxyribonuclease of the base excision repair pathway that
maintains genome stability. It was identified as a pivotal factor favoring tumor progression …

Simple Summary The dysregulation of Notch signaling plays an important role in cancer
development. Numerous attempts are made to modulate Notch signaling for positive …

Developing an efficient computational scheme for high-dimensional Bayesian variable
selection in generalised linear models and survival models has always been a challenging …

The identification of genetic factors that regulate the cancer immune microenvironment is
important for understanding the mechanism of tumor progression and establishing an …

Simple Summary Identifying biomarkers to guide immunotherapy regimens remains an
unmet clinical need in malignant pleural mesothelioma. A potential source of such markers …

Esophageal squamous cell carcinoma (ESCC) is one of the most frequent malignant tumors,
and the mechanisms underlying the anti-ferroptosis of esophageal cancer cells are still …

Simple Summary This review examines the current state of cancer databases and identifies
key needs in the field. The analysis of 71 databases reveals a lack of dedicated lipidomic …

The JADE family comprises three members encoded by individual genes and roles for these
proteins have been identified in chromatin remodeling, cell cycle progression, cell …

Simple Summary Breast cancer is not one homogeneous disease, but it includes many
subtypes that are identified in the clinical and research setting. The claudin-low subtype is a …

Somatic copy number alterations (SCNAs) are frequently observed in high-grade ovarian
serous carcinoma (HGOSC). However, their impact on gene expression levels has not been …