Pseudorabies virus (PRV) is a herpesvirus of swine, a member of the Alphaherpesvirinae
subfamily, and the etiological agent of Aujeszky's disease. This review describes the …

Primary infection by herpes simplex virus type 1 (HSV-1) can cause clinical symptoms in the
peripheral and central nervous system, upper respiratory tract, and gastrointestinal tract …

Our ability to manipulate the genetic constitution of the nervous system has come of age with
various technologies, including virus vectors that can efficiently deliver genes to neurons …

The clinical manifestations of herpes simplex virus infection generally involve a mild and
localized primary infection followed by asymptomatic (latent) infection interrupted …

Herpes simplex virus type 1 establishes latent infections in sensory neurons. During latency
only one locus, the latency-associated transcript (LAT), is abundantly transcribed. Several …

Publisher Summary Herpesviruses have been identified that infect nearly all groups of
vertebrates. This chapter focuses on the latency of α-herpesviruses. Several mammalian …

ABSTRACT A complex interaction has evolved between the host's peripheral nervous
system (PNS) and herpes simplex virus type 1 (HSV-1). Sensory neurons are permissive for …

Infection by herpes simplex virus type 1 (HSV‐1) can cause clinical symptoms in the
peripheral and central nervous system. Recurrent ocular shedding can lead to corneal …

Latent infections of neurons by herpes simplex virus form reservoirs of recurrent viral
infections that resist cure. In latently infected neurons, viral gene expression is severely …

Herpes simplex virus type 1 (HSV‐1) enters sensory neurons and can remain latent there
until reactivation. During latency restricted HSV‐1 gene expression takes place in the form of …