Lipases and lipolysis in the human digestive tract: where do we stand?

M Armand - Current Opinion in Clinical Nutrition & Metabolic Care, 2007 - journals.lww.com
A better knowledge of lipase structure and mode of action will help the development of new
natural inhibitors with fewer secondary effects. More intensive research in protein …

The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling

M Reisenberg, PK Singh… - … Transactions of the …, 2012 - royalsocietypublishing.org
The diacylglycerol lipases (DAGLs) hydrolyse diacylglycerol to generate 2-
arachidonoylglycerol (2-AG), the most abundant ligand for the CB1 and CB2 cannabinoid …

Structure and function of lysosomal phospholipase A2 and lecithin: cholesterol acyltransferase

A Glukhova, V Hinkovska-Galcheva, R Kelly… - Nature …, 2015 - nature.com
Abstract Lysosomal phospholipase A2 (LPLA2) and lecithin: cholesterol acyltransferase
(LCAT) belong to a structurally uncharacterized family of key lipid-metabolizing enzymes …

Improving the catalytic efficiency of Pseudomonas aeruginosa lipoxygenase by semi-rational design

C Pang, S Liu, G Zhang, J Zhou, G Du, J Li - Enzyme and Microbial …, 2023 - Elsevier
Lipoxygenase (LOX) catalyzes the peroxidation of unsaturated fatty acids to produce
hydroperoxides, which had been widely used in food, medicine and chemical industries due …

[HTML][HTML] The limitations of the current protein classification tools in identifying lipolytic features in putative bacterial lipase sequences

R Bashiri, TP Curtis, ID Ofiţeru - Journal of Biotechnology, 2022 - Elsevier
Metagenomics sequencing has generated millions of new protein sequences, most of them
with unknown functions. A relatively quick first step for function assignment is to use the …

[HTML][HTML] Las lipasas: enzimas con potencial para el desarrollo de biocatalizadores inmovilizados por adsorción interfacial

J González-Bacerio, VR Moreno-Medina… - Revista Colombiana …, 2010 - scielo.org.co
Las lipasas son enzimas con propiedades funcionales muy interesantes que permiten su
utilización práctica en diversos campos de las industrias agroquímica, farmacéutica, de …

Three-Dimensional Structure Determination of a Protein Supercomplex That Oxidizes Methane to Formaldehyde in Methylococcus capsulatus (Bath)

N Myronova, A Kitmitto, RF Collins, A Miyaji… - Biochemistry, 2006 - ACS Publications
The oxidation of methane to methanol in methanotrophs is catalyzed by the enzyme
methane monooxygenase (MMO). Two distinct forms of this enzyme exist, a soluble …

Discovery of a polyurethane-degrading enzyme from the gut bacterium of plastic-eating mealworms

J Ru, X Chen, X Dong, L Hu, J Zhang, Y Yang - Journal of Hazardous …, 2024 - Elsevier
Although numerous polyurethane (PU)-degrading enzymes were identified from a diverse
array of microorganisms in soil or compost, it is intriguing to investigate whether novel PU …

Les lipases sont des hydrolases atypiques: principales caractéristiques et applications

P Fickers, J Destain, P Thonart - Biotechnologie, agronomie, société et …, 2008 - orbi.uliege.be
Les triacylglycérol acyl-hydrolases, ou lipases, sont des enzymes atypiques de par leur
mécanisme d'action et leur spécificité de substrats. En fonction du micro-environnement de …

Improved catalytic performance and molecular insight for lipoxygenase from Enterovibrio norvegicus via directed evolution

B Zhang, H Chi, J Shen, Y Tao, Z Lu, F Lu… - … in Bioengineering and …, 2023 - frontiersin.org
Lipoxygenase (LOX) holds significant promise for food and pharmaceutical industries.
However, albeit its application has been hampered by low catalytic activity and suboptimal …