[HTML][HTML] Plant exosome-like nanovesicles: emerging therapeutics and drug delivery nanoplatforms

HA Dad, TW Gu, AQ Zhu, LQ Huang, LH Peng - Molecular Therapy, 2021 - cell.com
Plant exosome-like nanovesicles, being innately replete with bioactive lipids, proteins, RNA,
and other pharmacologically active molecules, offer unique morphological and …

Rho GTPase signaling in cancer progression and dissemination

E Crosas-Molist, R Samain… - Physiological …, 2022 - journals.physiology.org
Rho GTPases are a family of small G proteins that regulate a wide array of cellular
processes related to their key roles controlling the cytoskeleton. Cancer is a multistep …

Recent advancements in the use of exosomes as drug delivery systems

EJ Bunggulawa, W Wang, T Yin, N Wang… - Journal of …, 2018 - Springer
Extracellular vesicles (EVs) are the substances that are released by most types of cells and
have an important role in cell to cell communication. Among the most highly researched EVs …

Cancer stem cells as key drivers of tumour progression

AZ Ayob, TS Ramasamy - Journal of biomedical science, 2018 - Springer
Abstract Background Cancer stem cells (CSCs) are subpopulations of cancer cells sharing
similar characteristics as normal stem or progenitor cells such as self-renewal ability and …

Overview and update on extracellular vesicles: considerations on exosomes and their application in modern medicine

MA Di Bella - Biology, 2022 - mdpi.com
Simple Summary Exosomes are a subpopulation of extracellular vesicles, nanosized
particles, lipid bilayer-enclosed, naturally secreted from cells after the fusion of intracellular …

Systems biology of cancer metastasis

Y Suhail, MP Cain, K Vanaja, PA Kurywchak… - Cell systems, 2019 - cell.com
Cancer metastasis is no longer viewed as a linear cascade of events but rather as a series
of concurrent, partially overlapping processes, as successfully metastasizing cells assume …

[HTML][HTML] The amoeboid state as part of the epithelial-to-mesenchymal transition programme

V Graziani, I Rodriguez-Hernandez, O Maiques… - Trends in cell …, 2022 - cell.com
Cell migration is essential for many biological processes, while abnormal cell migration is
characteristic of cancer cells. Epithelial cells become motile by undergoing epithelial-to …

Exosomes derived from reparative M2-like macrophages prevent bone loss in murine periodontitis models via IL-10 mRNA

X Chen, Z Wan, L Yang, S Song, Z Fu, K Tang… - Journal of …, 2022 - Springer
Background Periodontitis is characterized by progressive inflammation and alveolar bone
loss resulting in tooth loss finally. Macrophages including pro-inflammatory M1-like …

[HTML][HTML] Extracellular vesicles from pancreatic cancer stem cells lead an intratumor communication network (EVNet) to fuel tumour progression

CF Ruivo, N Bastos, B Adem, I Batista, C Duraes… - Gut, 2022 - gut.bmj.com
Objective Intratumor heterogeneity drives cancer progression and therapy resistance.
However, it has yet to be determined whether and how subpopulations of cancer cells …

Extracellular vesicles as a novel source of biomarkers in liquid biopsies for monitoring cancer progression and drug resistance

MH Vasconcelos, HR Caires, A Ābols… - Drug Resistance …, 2019 - Elsevier
Cancer-derived extracellular vesicles (EVs) have been detected in the bloodstream and
other biofluids of cancer patients. They carry various tumor-derived molecules such as …