MicroRNAs are small double-stranded RNAs, which negatively regulate gene expression
and have been shown to have key roles in both chondrocyte development and cartilage …

MicroRNAs are small noncoding RNAs that can bind to the target sites in the 3'‐untranslated
region of messenger RNA to regulate posttranscriptional gene expression. Increasing …

Wound healing is one of the major global health concerns in patients with diabetes.
Overactivation of pro-inflammatory M1 macrophages is associated with delayed wound …

An imbalance in gene expressional events skewing chondrocyte anabolic and catabolic
pathways toward the latter causes an aberrant turnover and loss of extracellular matrix …

Background Our previous study revealed that the exosomal lncRNA H19 derived from
umbilical cord mesenchymal stem cells (UMSCs) plays a pivotal role in osteochondral …

Rationale: Osteoarthritis (OA) is the most common joint disease worldwide. Previous studies
have identified the imbalance between extracellular matrix (ECM) catabolism and anabolism …

Osteoarthritis (OA) is a degenerative whole joint disease, for which no preventative or
therapeutic biological interventions are available. This is likely due to the fact that OA …

This study was aimed to explore the role of miR‐29b‐3p and PGRN in chondrocyte
apoptosis and the initiation and progress of osteoarthritis (OA). Both miR‐29b‐3p and PGRN …

Abstract Background Mesenchymal stem cells (MSCs) are suspected to exert
neuroprotective effects in brain injury, in part through the secretion of extracellular vesicles …

The disabling degenerative disease osteoarthritis (OA) is prevalent among the global
population. Articular cartilage degeneration is a central feature of OA; therefore, a better …