Cardiovascular disease encompasses a range of conditions extending from myocardial
infarction to congenital heart disease, most of which are heritable. Enormous effort has been …

Cardiovascular diseases are the leading cause of death around the world. Despite the
larger number of genes and loci identified, the precise mechanisms by which these genes …

To elucidate the genetics of coronary artery disease (CAD) in the Japanese population, we
conducted a large-scale genome-wide association study of 168,228 individuals of Japanese …

Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is
largely based on genome-wide association study (GWAS) analysis of common SNPs …

Coronary artery disease (CAD) is the commonest cause of death. Here, we report an
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …

We performed a meta-analysis of 2 genome-wide association studies of coronary artery
disease comprising 1,515 cases and 5,019 controls followed by replication studies in 15,460 …

Cardiovascular diseases are leading causes for death worldwide. Genetic disposition jointly
with traditional risk factors precipitates their manifestation. Whereas the implications of a …

Dyes are one of the most common contaminants in industrial effluents, whose continuous
release into the environment has become an increasing global concern. In this work …

Thoracic aortic aneurysm (TAA) is a localized or diffuse dilatation of the thoracic aortas, and
causes many sudden deaths each year worldwide. However, there is no effective …

Atherosclerotic coronary artery disease (CAD) comprises a broad spectrum of clinical
entities that include asymptomatic subclinical atherosclerosis and its clinical complications …