L-arginine metabolism as pivotal interface of mutual host–microbe interactions in the gut

B Nüse, T Holland, M Rauh, RG Gerlach, J Mattner - Gut Microbes, 2023 - Taylor & Francis
ABSTRACT L-arginine (L-arg) is a versatile amino acid and a central intestinal metabolite in
mammalian and microbial organisms. Thus, L-arg participates as precursor of multiple …

Amino acids in cancer and cachexia: An integrated view

M Ragni, C Fornelli, E Nisoli, F Penna - Cancers, 2022 - mdpi.com
Simple Summary Cancer metabolism is an emerging field of investigation aimed at
identifying cancer cell vulnerabilities in order to define novel anti-cancer therapeutic …

Comprehensive insight into exploring the potential of microbial enzymes in cancer therapy: Progress, challenges, and opportunities: A review

FS Hassan, EM El-Fakharany, YA El-Maradny… - International Journal of …, 2024 - Elsevier
Microbial enzymes are crucial catalysts in various industries due to their versatility and
efficiency. The microbial enzymes market has recently expanded due to increased demand …

[HTML][HTML] Opportunities for nanomaterials in enzyme therapy

B Torres-Herrero, I Armenia, C Ortiz… - Journal of Controlled …, 2024 - Elsevier
In recent years, enzyme therapy strategies have rapidly evolved to catalyze essential
biochemical reactions with therapeutic potential. These approaches hold particular promise …

Cross-linked arginine deiminase aggregates for enhanced production of nutraceutical citrulline

A Kawatra, D Chhabra, P Gulati - Process Biochemistry, 2024 - Elsevier
Arginine deiminase (ADI) has been widely employed for the biological production of
nutraceutical citrulline. However, sub-optimal enzyme properties, operational instability, and …

Purification and characterization of L-arginine deiminase from Penicillium chrysogenum

HM El-Shora, NA El-Zawawy, MAA El-Rheem… - BMC microbiology, 2024 - Springer
Abstract L-arginine deiminase (ADI, EC 3.5. 3.6) hydrolyzes arginine to ammonia and
citrulline which is a natural supplement in health care. ADI was purified from Penicillium …

Application of phytochemicals in therapeutic, food, flavor, and cosmetic industries

A Kawatra, S Gupta, R Dhankhar, P Singh… - … : Plant Metabolomics and …, 2023 - Springer
Over the past centuries, the “chemodiversity” of the kingdom plantae has gained utmost
importance in securing mankind's future and overall well-being of people across the globe …

Nano‐and Micro‐Platforms in Therapeutic Proteins Delivery for Cancer Therapy: Materials and Strategies

H Han, HA Santos - Advanced Materials, 2024 - Wiley Online Library
Proteins have emerged as promising therapeutics in oncology due to their great specificity.
Many treatment strategies are developed based on protein biologics, such as …

Streptococcal arginine deiminase inhibits T lymphocyte differentiation in vitro

EA Starikova, JT Mammedova, A Ozhiganova… - Microorganisms, 2023 - mdpi.com
Pathogenic microbes use arginine-metabolizing enzymes as an immune evasion strategy. In
this study, the impact of streptococcal arginine deiminase (ADI) on the human peripheral …

Recent trends in targeted delivery of smart nanocarrier-based microbial enzymes for therapeutic applications

N Jangra, A Kawatra, B Datten, S Gupta, P Gulati - Drug Discovery Today, 2024 - Elsevier
Smart carrier-based immobilization has widened the use of enzymes for the treatment of
several disorders. Large surface areas, tunable morphology, and surface modification ability …