Ionic liquids: new forms of active pharmaceutical ingredients with unique, tunable properties
JL Shamshina, RD Rogers - Chemical Reviews, 2023 - ACS Publications
This Review aims to summarize advances over the last 15 years in the development of
active pharmaceutical ingredient ionic liquids (API-ILs), which make up a prospective game …
active pharmaceutical ingredient ionic liquids (API-ILs), which make up a prospective game …
Biological activity of ionic liquids and their application in pharmaceutics and medicine
KS Egorova, EG Gordeev, VP Ananikov - Chemical reviews, 2017 - ACS Publications
Ionic liquids are remarkable chemical compounds, which find applications in many areas of
modern science. Because of their highly tunable nature and exceptional properties, ionic …
modern science. Because of their highly tunable nature and exceptional properties, ionic …
Biocompatible ionic liquids and their applications in pharmaceutics
Ionic liquids (ILs) have been used as solvents or materials, or both, in many applications,
including pharmaceutics and medicine due to their exceptional properties consisting of the …
including pharmaceutics and medicine due to their exceptional properties consisting of the …
50 years of oral lipid-based formulations: provenance, progress and future perspectives
Lipid based formulations (LBF) provide well proven opportunities to enhance the oral
absorption of drugs and drug candidates that sit close to, or beyond, the boundaries of …
absorption of drugs and drug candidates that sit close to, or beyond, the boundaries of …
Ionic liquids as a potential tool for drug delivery systems
N Adawiyah, M Moniruzzaman, S Hawatulaila… - …, 2016 - pubs.rsc.org
The pharmaceutical industries face a series of challenges in the delivery of many newly
developed drug molecules because of their low solubility, bioavailability, stability and …
developed drug molecules because of their low solubility, bioavailability, stability and …
Chemistry: Develop ionic liquid drugs
Chemistry: Develop ionic liquid drugs | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …
nature.com. You are using a browser version with limited support for CSS. To obtain the best …
Ionic liquids with N-methyl-2-pyrrolidonium cation as an enhancer for topical drug delivery: Synthesis, characterization, and skin-penetration evaluation
The development of non-toxic ionic liquid-based active pharmaceutical ingredients (IL-APIs)
for effective topical drug delivery is still challenging. The properties of IL-APIs can be …
for effective topical drug delivery is still challenging. The properties of IL-APIs can be …
Transformation of hydrophilic drug into oil-miscible ionic liquids for transdermal drug delivery
R Md Moshikur, IM Shimul, S Uddin… - … Applied Materials & …, 2022 - ACS Publications
The transdermal delivery of hydrophilic drugs remains challenging owing to their poor ability
to permeate the skin; formulation with oil media is difficult without adding chemical …
to permeate the skin; formulation with oil media is difficult without adding chemical …
Ionic liquids with methotrexate moieties as a potential anticancer prodrug: Synthesis, characterization and solubility evaluation
The technological utility of active pharmaceutical ingredients (APIs) is enormously improved
when they are converted into ionic liquids (ILs). API-ILs possess better aqueous solubility …
when they are converted into ionic liquids (ILs). API-ILs possess better aqueous solubility …
Imidazole and imidazolium antibacterial drugs derived from amino acids
A Valls, JJ Andreu, E Falomir, SV Luis, E Atrián-Blasco… - Pharmaceuticals, 2020 - mdpi.com
The antibacterial activity of imidazole and imidazolium salts is highly dependent upon their
lipophilicity, which can be tuned through the introduction of different hydrophobic …
lipophilicity, which can be tuned through the introduction of different hydrophobic …