Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …

Promotion of good mental health, prevention, and early intervention before/at the onset of
mental disorders improve outcomes. However, the range and peak ages at onset for mental …

Importance Estimating the current likelihood of transitioning from a clinical high risk for
psychosis (CHR-P) to psychosis holds paramount importance for preventive care and …

Preventive approaches have latterly gained traction for improving mental health in young
people. In this paper, we first appraise the conceptual foundations of preventive psychiatry …

The endocannabinoid system (ECS) is a widespread neuromodulatory network involved in
the developing central nervous system as well as playing a major role in tuning many …

The authors examine US-based evidence that connects characteristics of the social
environment with outcomes across the psychosis continuum, from psychotic experiences to …

The current management of patients with primary psychosis worldwide is often remarkably
stereotyped. In almost all cases an antipsychotic medication is prescribed, with second …

Schizophrenia substantially contributes to the burden of mental disorders. Schizophrenia's
burden and epidemiological estimates in some countries have been published, but updated …

The immune system is generally known to be the primary defense mechanism against
pathogens. Any pathological conditions are reflected in anomalies in the immune system …

Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …