For more than four decades, the free-living nematode Caenorhabditis elegans has been
extensively used in anthelmintic research. Classic genetic screens and heterologous …

Nematodes are presumably the most abundant Metazoa on Earth, and can even be found in
some of the most hostile environments of our planet. Various types of hypobiosis evolved to …

Animals with complex nervous systems demand sleep for memory consolidation and
synaptic remodeling. Here, we show that, although the Caenorhabditis elegans nervous …

The impact of the host immune environment on parasite transcription and fitness is currently
unknown. It is widely held that hookworm infections have an immunomodulatory impact on …

The antagonistic pleiotropy theory of aging proposes that genes enhancing fitness in early
life limit the lifespan, but the molecular evidence remains underexplored. By profiling …

Many cell types display the remarkable ability to alter their cellular phenotype in response to
specific external or internal signals. Such phenotypic plasticity is apparent in the nematode …

Apical extracellular matrices (aECMs) coat the exposed surfaces of animal bodies to shape
tissues, influence social interactions, and protect against pathogens and other …

Natural environments are highly dynamic, and this complexity challenges animals to
accurately integrate external cues to shape their responses. Adaptive developmental …

The pine wood nematode Bursaphelenchus xylophilus is the causal agent of pine wilt
disease, one of the most devastating forest diseases in East Asian and West European …

Neuropeptides regulate animal physiology and behavior, making them widely studied
targets of functional genetics research. While the field often relies on differential-omics …