An important role for bioenergetic dysfunction is increasingly emerging to potentially explain
the paradox of clinical and biochemical organ failure in sepsis yet minimal cell death …

Sepsis is one of the main causes of death among critically ill patients. Sepsis pathogenesis
includes infection by gram-negative and gram-positive bacteria, fungi, or both; exacerbated …

Rationale: Cardiac remodeling and subsequent heart failure remain critical issues after
myocardial infarction despite improved treatment and reperfusion strategies. Recently …

Background The role of assessment of myocardial viability in identifying patients with
ischemic cardiomyopathy who might benefit from surgical revascularization remains …

Background The assessment of myocardial viability has been used to identify patients with
coronary artery disease and left ventricular dysfunction in whom coronary-artery bypass …

A substantial proportion of patients with acute myocardial infarction develop clinical heart
failure, which remains a common and major healthcare burden. It has been shown that in …

Ischemic cardiomyopathy results from the combination of scar with fibrosis replacement and
areas of dysfunctional but viable myocardium that may improve contractile function with …

Objectives”, explains how to select and use various test methods for evaluating disease
states, the prognosis, and the effects of treatment. References to the literature published …

Exercise testing has an established role in the evaluation of patients with valvular heart
disease and can aid clinical decision making. Because symptoms may develop slowly and …

Background Myocardial revascularization has been advocated to improve myocardial
function and prognosis in ischemic cardiomyopathy (ICM). We discuss the evidence for …