The role of myeloperoxidase in biomolecule modification, chronic inflammation, and disease

MJ Davies, CL Hawkins - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: The release of myeloperoxidase (MPO) by activated leukocytes is critical in
innate immune responses. MPO produces hypochlorous acid (HOCl) and other strong …

Hyaluronan and reactive oxygen species signaling—novel cues from the matrix?

A Berdiaki, M Neagu, I Spyridaki, A Kuskov, S Perez… - Antioxidants, 2023 - mdpi.com
Hyaluronan (HA) is a naturally occurring non-sulfated glycosaminoglycan (GAG) localized to
the cell surface and the tissue extracellular matrix (ECM). It is composed of disaccharides …

Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention

MJ Davies - Journal of clinical biochemistry and nutrition, 2010 - jstage.jst.go.jp
抄録 There is considerable interest in the role that mammalian heme peroxidase enzymes,
primarily myeloperoxidase, eosinophil peroxidase and lactoperoxidase, may play in a wide …

Dispersibility‐dependent biodegradation of graphene oxide by myeloperoxidase

R Kurapati, J Russier, MA Squillaci, E Treossi… - Small, 2015 - Wiley Online Library
Understanding human health risk associated with the rapidly emerging graphene‐based
nanomaterials represents a great challenge because of the diversity of applications and the …

Mammalian heme peroxidases: from molecular mechanisms to health implications

MJ Davies, CL Hawkins, DI Pattison… - Antioxidants & redox …, 2008 - liebertpub.com
A marked increase in interest has occurred over the last few years in the role that
mammalian heme peroxidase enzymes, primarily myeloperoxidase, eosinophil peroxidase …

Net-1, 2-hydrogen atom transfer of amidyl radicals: Toward the synthesis of 1, 2-diamine derivatives

Y Jiang, D Liu, ME Rotella, G Deng, Z Liu… - Journal of the …, 2023 - ACS Publications
Hydrogen atom transfer (HAT) processes are among the most useful approaches for the
selective construction of C (sp3)–C (sp3) bonds. 1, 5-HAT with heteroatom-centered radicals …

Detection and characterisation of radicals using electron paramagnetic resonance (EPR) spin trapping and related methods

MJ Davies - Methods, 2016 - Elsevier
Electron paramagnetic resonance (EPR) spectroscopy (also known as electron spin
resonance, ESR, or electron magnetic resonance, EMR, spectroscopy) is often described as …

Oxidative release of natural glycans for functional glycomics

X Song, H Ju, Y Lasanajak, MR Kudelka, DF Smith… - Nature …, 2016 - nature.com
Glycans have essential roles in biology and the etiology of many diseases. A major hurdle in
studying glycans through functional glycomics is the lack of methods to release glycans from …

Oxidative depolymerization of polysaccharides by reactive oxygen/nitrogen species

J Duan, DL Kasper - Glycobiology, 2011 - academic.oup.com
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are constantly
produced and are tightly regulated to maintain a redox balance (or homeostasis) together …

Mechanistic overview of reactive species-induced degradation of the endothelial glycocalyx during hepatic ischemia/reperfusion injury

RF van Golen, TM van Gulik, M Heger - Free Radical Biology and Medicine, 2012 - Elsevier
Endothelial cells are covered by a delicate meshwork of glycoproteins known as the
glycocalyx. Under normophysiological conditions the glycocalyx plays an active role in …