Cadmium as a testicular toxicant: A Review
JK Bhardwaj, H Panchal, P Saraf - Journal of Applied …, 2021 - Wiley Online Library
Cadmium (Cd) is a toxic heavy metal with no known biological functions in the human body.
Due to a considerably long biological half‐life and very low rate of excretion, accumulation …
Due to a considerably long biological half‐life and very low rate of excretion, accumulation …
[HTML][HTML] The role of toxic metals and metalloids in Nrf2 signaling
Nuclear factor erythroid 2-related factor 2 (Nrf2), an emerging regulator of cellular resistance
to oxidants, serves as one of the key defensive factors against a range of pathological …
to oxidants, serves as one of the key defensive factors against a range of pathological …
Protocatechuic acid mitigates cadmium-induced neurotoxicity in rats: Role of oxidative stress, inflammation and apoptosis
EM Al Olayan, AS Aloufi, OD AlAmri, H Ola… - Science of the total …, 2020 - Elsevier
Environmental and occupational exposure to heavy metals, including cadmium (Cd), is
associated with extremely adverse impacts to living systems. Antioxidant agents are …
associated with extremely adverse impacts to living systems. Antioxidant agents are …
Diacerein downregulates NLRP3/Caspase-1/IL-1β and IL-6/STAT3 pathways of inflammation and apoptosis in a rat model of cadmium testicular toxicity
AA Fouad, AM Abdel-Aziz, AAH Hamouda - Biological Trace Element …, 2020 - Springer
The potential gonadal protective effect of diacerein (DCN) and its underlying mechanisms
were studied in a rat model of cadmium-induced testicular toxicity. The rats received DCN …
were studied in a rat model of cadmium-induced testicular toxicity. The rats received DCN …
Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage
Cadmium (Cd) is an environmental contaminant found in soil, water, and food, and can
cause oxidative stress and male reproductive damage. During puberty, the male …
cause oxidative stress and male reproductive damage. During puberty, the male …
Ferulic acid influences Nrf2 activation to restore testicular tissue from cadmium‐induced oxidative challenge, inflammation, and apoptosis in rats
Here, we examined the protective effect of ferulic acid (FA) on cadmium chloride (CdCl2)‐
mediated reproductive toxicity in male rats. Animals were divided into four groups: control …
mediated reproductive toxicity in male rats. Animals were divided into four groups: control …
Discovery of a potent glutathione peroxidase 4 inhibitor as a selective ferroptosis inducer
C Xu, Z Xiao, J Wang, H Lai, T Zhang… - Journal of Medicinal …, 2021 - ACS Publications
Potent and selective ferroptosis regulators promote an intensive understanding of the
regulation and mechanisms underlying ferroptosis, which is highly associated with various …
regulation and mechanisms underlying ferroptosis, which is highly associated with various …
[HTML][HTML] A flavonoid-rich extract from bergamot juice, alone or in association with curcumin and resveratrol, shows protective effects in a murine model of cadmium …
It is known that cadmium damages testis structure and functionality. We examined the effects
of nutraceuticals such as a flavonoid-rich extract of bergamot juice (BJe), alone or in …
of nutraceuticals such as a flavonoid-rich extract of bergamot juice (BJe), alone or in …
Luteolin protects against testicular injury induced by lead acetate by activating the Nrf2/HO‐1 pathway
WA AL‐Megrin, S Alomar, AF Alkhuriji… - IUBMB …, 2020 - Wiley Online Library
Lead (Pb) is a toxic heavy metal that is harmful to humans, especially male reproductive
organs. Luteolin (LUT) is a naturally occurring flavonoid with numerous biological activities …
organs. Luteolin (LUT) is a naturally occurring flavonoid with numerous biological activities …
Senna alexandrina extract supplementation reverses hepatic oxidative, inflammatory, and apoptotic effects of cadmium chloride administration in rats
X Wang, T Wang, T Pan, M Huang, W Ren, G Xu… - … Science and Pollution …, 2020 - Springer
Senna alexandrina is traditionally used for its antioxidant and anti-inflammatory properties,
but little information is available concerning its potential protective effects against cadmium …
but little information is available concerning its potential protective effects against cadmium …