Cytotoxicity and mechanism of action of metal complexes: An overview
After the discovery of cisplatin, many metal compounds were investigated for the therapy of
diseases, especially cancer. The high therapeutic potential of metal-based compounds is …
diseases, especially cancer. The high therapeutic potential of metal-based compounds is …
An overview on the recent developments of 1, 2, 4-triazine derivatives as anticancer compounds
S Cascioferro, B Parrino, V Spano, A Carbone… - European Journal of …, 2017 - Elsevier
The synthesis, the antitumor activity, the SAR and, whenever described, the possible mode
of action of 1, 2, 4-triazine derivatives, their N-oxides, N, N′-dioxides as well as the benzo …
of action of 1, 2, 4-triazine derivatives, their N-oxides, N, N′-dioxides as well as the benzo …
Mechanistic competitive binding interaction study between olmutinib and colchicine with model transport protein using spectroscopic and computer simulation …
Drug-drug interactions are due to the binding of a drug to plasma proteins displacing
another plasma protein-bound drug. Two ligands, olmutinib (OLM) and colchicine (COL) …
another plasma protein-bound drug. Two ligands, olmutinib (OLM) and colchicine (COL) …
Binding of colchicine and ascorbic acid (vitamin C) to bovine serum albumin: An in-vitro interaction study using multispectroscopic, molecular docking and molecular …
Two or more drugs are prescribed commonly to patients depending on their physical health
conditions. Concomitant drugs might lead to specific drug-drug interactions with serum …
conditions. Concomitant drugs might lead to specific drug-drug interactions with serum …
A new zinc (II) complex of 2-benzoimidazoledisulfide ligand: synthesis, X-ray crystallographic structure, investigation of CT-DNA and BSA interaction by spectroscopic …
F Mohammadlou, H Mansouri-Torshizi… - … of Photochemistry and …, 2023 - Elsevier
This study reports a new zinc (II) complex based on 2-mercaptobenzimidazole ligand. It was
synthesized and characterized by UV–visible and Fourier transform infrared spectroscopy …
synthesized and characterized by UV–visible and Fourier transform infrared spectroscopy …
Probing the biomolecular (DNA/BSA) interaction by new Pd (II) complex via in-depth experimental and computational perspectives: Synthesis, characterization …
M Feizi-Dehnayebi, E Dehghanian… - Journal of the Iranian …, 2022 - Springer
Scientists should not forget that the rate of death as a result of cancer is far more than that of
other diseases like influenza or coronavirus (COVID-19), so the research in this field is of …
other diseases like influenza or coronavirus (COVID-19), so the research in this field is of …
Azoimine quinoline derivatives: Synthesis, classical and electrochemical evaluation of antioxidant, anti-inflammatory, antimicrobial activities and the DNA/BSA binding
Four azoimine quinoline derivatives namely (1Z)-N'-(4-fluorophenyl)-2-oxo-N-quinolin-8-
ylpropanehydrazonamide (H 2 LF),(1Z)-2-oxo-N′-phenyl-N-quinolin-8-ylpropane …
ylpropanehydrazonamide (H 2 LF),(1Z)-2-oxo-N′-phenyl-N-quinolin-8-ylpropane …
Quinoline functionalized schiff base silver (I) complexes: interactions with biomolecules and in vitro cytotoxicity, antioxidant and antimicrobial activities
A series of fifteen silver (I) quinoline complexes Q1–Q15 have been synthesized and studied
for their biological activities. Q1–Q15 were synthesized from the reactions of quinolinyl Schiff …
for their biological activities. Q1–Q15 were synthesized from the reactions of quinolinyl Schiff …
[HTML][HTML] A novel Schiff base derived from the gabapentin drug and copper (II) complex: Synthesis, characterization, interaction with DNA/protein and cytotoxic activity
Z Shokohi-Pour, H Chiniforoshan… - … of Photochemistry and …, 2016 - Elsevier
A novel Schiff base [C 20 H 23 NO 3], has been prepared and characterized using FT-IR, UV–
vis, 1 H NMR spectroscopy, elemental analysis and X-ray crystallography. A copper (II) …
vis, 1 H NMR spectroscopy, elemental analysis and X-ray crystallography. A copper (II) …
Targeting of DNA molecules, BSA/c-Met tyrosine kinase receptors and anti-proliferative activity of bis (terpyridine) copper (II) complexes
A series of homoleptic bis (terpyridine) copper (II) complexes of the type [Cu (L1–5) 2] Cl2 (1–
5), where L1–5= 4′-(4-substituted)-2, 2′: 6′, 2′′-terpyridines, have been synthesized …
5), where L1–5= 4′-(4-substituted)-2, 2′: 6′, 2′′-terpyridines, have been synthesized …