Pharmacological treatment is not very effective for neuropathic pain (NP). A progressive
decrease in the estimated effect of NP drugs has been reported, giving rise to an increase in …

Anticonvulsant drugs such as pregabalin (PGB) and lacosamide (LCM), exhibit potent
analgesic effects in diabetic neuropathy; however, their possible role/mechanisms in …

Peripheral neuropathy is a common adverse effect observed during the use of paclitaxel
(PTX) as chemotherapy. The present investigation was directed to estimate the modulatory …

Chemotherapy-induced peripheral neuropathy is a common factor in limiting therapy which
can result in therapy cessation or dose reduction. Gabapentin, a calcium channel inhibitor …

Chemotherapy-induced neuropathic pain (CINP), a condition with unmet treatment needs,
affects over half of cancer patients treated with chemotherapeutics. Researchers have …

The clinical pathology of Taxol-induced peripheral neuropathy (TIPN), characterized by loss
of sensory sensitivity and pain, is mirrored in a preclinical pharmacological mice model in …

Neuropathic pain is a worldwide health problem with no consensus regarding its optimal
therapy. This study compared the analgesic effect and gastric, hepatic, and renal safety of …

Background: Paclitaxel is a drug used to treat cancer, but it causes neuropathic pain and
peripheral neuropathy. One of the causes of these effects of paclitaxel on nerve tissue is …

Pharmacological treatment is poorly effective for neuropathic pain (NP). A progressive
decrease in the estimated effect of NP drugs has been reported, giving rise to an increase in …

In this study, the potential protective effects of chrysin, an important flavonoid, against
paclitaxel-induced cell toxicity in the SH-SY5Y nerve cell line as an in vitro model, were …