The aim of the current study was to evaluate the effects of a mixture of thirteen common
chemicals on rats, after a one-year exposure to doses around the acceptable daily intake …

Adhesion of circulating tumor cells to vascular endothelium is mediated by specialized
molecules that are functional under shear forces exerted by hematogenous flow. Endothelial …

Dissemination of multiple myeloma into the bone marrow proceeds through sequential steps
mediated by a variety of adhesion molecules and chemokines that eventually results in the …

Cutaneous T-cell lymphoma (CTCL) such as Sézary syndrome (SS) or Mycosis Fungoides
(MF) correspond to an abnormal infiltration of T lymphocytes in the skin. CTCL cells have a …

While human Tregs hold immense promise for immunotherapy, their biologic variability
poses challenges for clinical use. Here, we examined clinically-relevant activities of defined …

Simple Summary Platelet cloaking of tumor cells has been shown to play an important role
in tumor metastasis and immune evasion. Multiple myeloma is a tumor of the plasma cells …

In chronic myelogenous (CML) and chronic eosinophilic leukemia (CEL), neoplastic cells
spread via the circulation into various extramedullary organs. As E-and P-selectin constitute …

Background The E-selectin ligands expressed by cancer cells mediate adhesion of
circulating cancer cells to endothelial cells, as well as within tissue microenvironments …

Stem bromelain, a cysteine protease isolated from pineapples, is a natural anti-inflammatory
treatment, yet its mechanism of action remains unclear. Curious as to whether bromelain …

Neuropsychiatric systemic lupus erythematosus is an autoimmune disorder characterized by
an irregular exchange between the central nervous system and the immune system, leading …