NLRP3 inflammasome is a multiprotein complex involved in host immune response─ which
exerts various biological effects by mediating the maturation and secretion of IL-1β and IL …

Autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), primary sclerosing cholangitis
(PSC), and IgG4-related sclerosing cholangitis (IgG4-SC) are the four main forms of …

Sulfated fucans are important marine polysaccharides with various bioactivities. Fucanases
are desirable tools for the structural elucidations and oligosaccharides preparation of …

Staphylococcus enterotoxin B (SEB) is one of the primary virulence factors of
Staphylococcus aureus but there is still a lack of targeted drugs. SEB activates immune cells …

The search for bioactive compounds in natural products holds promise for discovering new
pharmacologically active molecules. This study explores the anti-inflammatory potential of …

Simple Summary Protein structure prediction using computer algorithms has long been a
challenge; however, the recent introduction of algorithms like AlphaFold2 and ESMFold to …

High performance computing (HPC) is taking an increasingly important place in drug
discovery. It makes possible the simulation of complex biochemical systems with high …