Promising antigens for the new frontier of targeted immunotherapy in multiple myeloma
SF Cho, L Xing, KC Anderson, YT Tai - Cancers, 2021 - mdpi.com
Simple Summary Defining the specificity and biological sequalae induced by receptors
differentiated expressed in multiple myeloma cells are critical for the development of …
differentiated expressed in multiple myeloma cells are critical for the development of …
ImmunoPET imaging of hematological malignancies: From preclinical promise to clinical reality
Y Dun, G Huang, J Liu, W Wei - Drug Discovery Today, 2022 - Elsevier
Immuno-positron emission tomography (immunoPET) imaging is a paradigm-shifting
imaging technique for whole-body and all-lesion tumor detection, based on the combined …
imaging technique for whole-body and all-lesion tumor detection, based on the combined …
CS1 CAR-T targeting the distal domain of CS1 (SLAMF7) shows efficacy in high tumor burden myeloma model despite fratricide of CD8+ CS1 expressing CAR-T cells
J O'Neal, JK Ritchey, ML Cooper, J Niswonger… - Leukemia, 2022 - nature.com
Despite improvement in treatment options for myeloma patients, including targeted
immunotherapies, multiple myeloma remains a mostly incurable malignancy. High CS1 …
immunotherapies, multiple myeloma remains a mostly incurable malignancy. High CS1 …
Single-domain antibody theranostics on the horizon
W Wei, MH Younis, X Lan, J Liu… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Single-domain antibody (sdAb) is among the most promising vectors for developing
molecular imaging tracers. Several sdAb tracers targeting human epidermal growth factor …
molecular imaging tracers. Several sdAb tracers targeting human epidermal growth factor …
Development of a [89Zr]Zr-labeled Human Antibody using a Novel Phage-displayed Human scFv Library
Abstract Purpose: Tax-interacting protein 1 (TIP1) is a cancer-specific radiation-inducible
cell surface antigen that plays a role in cancer progression and resistance to therapy. This …
cell surface antigen that plays a role in cancer progression and resistance to therapy. This …
Selective PET imaging of CXCR4 using the Al18F-labeled antagonist LY2510924
MA Spahn, TV Loy, S Celen, M Koole… - European Journal of …, 2024 - Springer
Background [68 Ga] PentixaFor detects CXC chemokine receptor type 4 (CXCR4)
overexpression in various malignancies, such as multiple myeloma and non-Hodgkin …
overexpression in various malignancies, such as multiple myeloma and non-Hodgkin …
In vivo quantitative assessment of therapeutic response to bortezomib therapy in disseminated animal models of multiple myeloma with [18F]FDG and [64Cu]Cu …
A Ghai, N Fettig, F Fontana, J DiPersio, M Rettig… - EJNMMI research, 2021 - Springer
Background Multiple myeloma (MM) is a disease of cancerous plasma cells in the bone
marrow. Imaging-based timely determination of therapeutic response is critical for improving …
marrow. Imaging-based timely determination of therapeutic response is critical for improving …
Recent developments on the application of molecular probes in multiple myeloma: Beyond [18F]FDG
S Zhang, J Shang, W Ye, T Zhao, H Xu… - … in Bioengineering and …, 2022 - frontiersin.org
Multiple myeloma (MM) is a neoplastic plasma cell proliferative disorder characterized by
various osteolytic bone destruction as a radiological morphological marker. Functional …
various osteolytic bone destruction as a radiological morphological marker. Functional …
Determining Binding Affinity (KD) of Radiolabeled Antibodies to Immobilized Antigens
E Belitzky, A Cavaliere, K Rajabimoghadam… - JoVE (Journal of …, 2022 - jove.com
Determining binding affinity (KD) is an important aspect of the characterization of
radiolabeled antibodies (rAb). Typically, binding affinity is represented by the equilibrium …
radiolabeled antibodies (rAb). Typically, binding affinity is represented by the equilibrium …
Biotechnological Aspects of Siderophore Biosynthesis by Actinobacteria
A Maier, C Mügge, D Tischler - Natural Products from Actinomycetes …, 2022 - Springer
Actinobacteria (Actinomycetes) comprise diverse and ancient phyla of the bacteria with
important properties for biotechnology. Large genomes and (mega) plasmids pose a …
important properties for biotechnology. Large genomes and (mega) plasmids pose a …