Nanoparticles for cancer therapy: current progress and challenges

S Gavas, S Quazi, TM Karpiński - Nanoscale research letters, 2021 - Springer
Cancer is one of the leading causes of death and morbidity with a complex pathophysiology.
Traditional cancer therapies include chemotherapy, radiation therapy, targeted therapy, and …

Nanoparticle-based drug delivery in cancer therapy and its role in overcoming drug resistance

Y Yao, Y Zhou, L Liu, Y Xu, Q Chen, Y Wang… - Frontiers in molecular …, 2020 - frontiersin.org
Nanotechnology has been extensively studied and exploited for cancer treatment as
nanoparticles can play a significant role as a drug delivery system. Compared to …

Extracellular vesicles‐derived hybrid nanoplatforms for amplified CD47 blockade‐based cancer immunotherapy

L Tang, Y Yin, Y Cao, C Fu, H Liu, J Feng… - Advanced …, 2023 - Wiley Online Library
Immunomodulation of tumor‐associated macrophages (TAMs) into tumor‐inhibiting M1‐like
phenotype is a promising but challenging strategy. Cleverly, tumor cells overexpress CD47 …

Understanding and targeting the disease‐related RNA binding protein human antigen R (HuR)

CW Schultz, R Preet, T Dhir, DA Dixon… - Wiley Interdisciplinary …, 2020 - Wiley Online Library
Altered gene expression is a characteristic feature of many disease states such as
tumorigenesis, and in most cancers, it facilitates cancer cell survival and adaptation …

Recent advances in nanoparticle-based cancer drug and gene delivery

N Amreddy, A Babu, R Muralidharan… - Advances in cancer …, 2018 - Elsevier
Effective and safe delivery of anticancer agents is among the major challenges in cancer
therapy. The majority of anticancer agents are toxic to normal cells, have poor bioavailability …

[HTML][HTML] RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer

M Mehta, R Raguraman, R Ramesh… - Advanced drug delivery …, 2022 - Elsevier
Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …

HuR as a molecular target for cancer therapeutics and immune-related disorders

M Majumder, P Chakraborty, S Mohan… - Advanced drug delivery …, 2022 - Elsevier
The control of eukaryotic gene expression occurs at multiple levels, from transcription to
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …

Folic acid-functionalized, condensed magnetic nanoparticles for targeted delivery of doxorubicin to tumor cancer cells overexpressing the folate receptor

A Angelopoulou, A Kolokithas-Ntoukas, C Fytas… - ACS …, 2019 - ACS Publications
This study concerns the development of folic acid (FA)-functionalized iron oxide condensed
colloidal magnetic clusters for a more selective delivery of doxorubicin (DOX) to tumor …

Nanosomes carrying doxorubicin exhibit potent anticancer activity against human lung cancer cells

A Srivastava, N Amreddy, A Babu, J Panneerselvam… - Scientific reports, 2016 - nature.com
Successful chemotherapeutic intervention for management of lung cancer requires an
efficient drug delivery system. Gold nanoparticles (GNPs) can incorporate various …

Formulation design, statistical optimization, and in vitro evaluation of a naringenin nanoemulsion to enhance apoptotic activity in A549 lung cancer cells

S Md, NA Alhakamy, HM Aldawsari, M Husain, S Kotta… - Pharmaceuticals, 2020 - mdpi.com
Naringenin (NAR), a flavonoid mainly found in citrus and grapefruits, has proven anti-cancer
activities. However, the poor water solubility and low bioavailability of NAR limits its use as a …