Condensation-Based Methods for the C–H Bond Functionalization of Amines
W Chen, D Seidel - Synthesis, 2021 - thieme-connect.com
This review aims to provide a comprehensive overview of condensation-based methods for
the C–H bond functionalization of amines that feature azomethine ylides as key …
the C–H bond functionalization of amines that feature azomethine ylides as key …
Dearomatization–rearomatization strategy for reductive cross-coupling of indoles with ketones in water
N-Alkylation of indoles is one of the important pathways for the construction of various
biologically active indole molecules. Using ketones as N-alkylation reagent for indoles has …
biologically active indole molecules. Using ketones as N-alkylation reagent for indoles has …
Inhibition effect of rhodanines containing benzene moieties on pentose phosphate pathway enzymes and molecular docking
Recently, inhibition studies of pentose phosphate pathway (PPP) enzymes have come out
as an encouraging approach for pharmacological intervention in a variety of disorders. For …
as an encouraging approach for pharmacological intervention in a variety of disorders. For …
A facile one-pot method to synthesise 2-alkylated indole and 2, 2′-bis (indolyl) methane derivatives using ketones as electrophiles and their anion sensing ability
S Bayindir, N Saracoglu - RSC advances, 2016 - pubs.rsc.org
Indole derivatives are of great importance because of their biological activity and application
in technology. This study explores the synthesis of 2-alkylated indoles derivatives and 2, 2 …
in technology. This study explores the synthesis of 2-alkylated indoles derivatives and 2, 2 …
The synthesis of new oxindoles as analogs of natural product 3,3-bis(indolyl)oxindole and in vitro evaluation of the enzyme activity of G6PD and 6PGD
Natural and synthetic derivatives that contain an indole core are being used in medical
treatments and technological processes. Therefore, the development of new synthetic …
treatments and technological processes. Therefore, the development of new synthetic …
The synthesis of N‐benzoylindoles as inhibitors of rat erythrocyte glucose‐6‐phosphate dehydrogenase and 6‐phosphogluconate dehydrogenase
Abstract Glucose‐6‐phosphate dehydrogenase (G6PD) and 6‐phosphogluconate
dehydrogenase (6PGD) play an important function in various biochemical processes as they …
dehydrogenase (6PGD) play an important function in various biochemical processes as they …
1, 3-Dipolar cycloaddition reaction of indoles with tosyl azide, subsequent dehydroaromatization and ring-opening cascade: a computational study
The mechanism of the reaction of N-methylindoles with tosyl azide to afford 3-diazoindolin-2-
imines and 2-iminoindolines has been studied computationally at the DFT M06/6-311G (d …
imines and 2-iminoindolines has been studied computationally at the DFT M06/6-311G (d …
Domino Aza-Michael-SNAr-Heteroaromatization Route to C5-Substituted 1-Alkyl-1H-Indole-3-Carboxylic Esters
E Ametsetor, S Farthing, RA Bunce - Molecules, 2022 - mdpi.com
A new synthesis of C5-substituted 1-alkyl-1 H-indole-3-carboxylic esters is reported. A series
of methyl 2-arylacrylate aza-Michael acceptors were prepared with aromatic substitution to …
of methyl 2-arylacrylate aza-Michael acceptors were prepared with aromatic substitution to …
Selective Iron Catalyzed Synthesis of N‐Alkylated Indolines and Indoles
J Wu, S Tongdee, M Cordier… - Chemistry–A European …, 2022 - Wiley Online Library
Whereas iron catalysts usually promote catalyzed C3‐alkylation of indole derivatives via a
borrowing‐hydrogen methodology using alcohols as the electrophilic partners, this …
borrowing‐hydrogen methodology using alcohols as the electrophilic partners, this …
Bismuth nitrate-promoted disproportionative condensation of indoles with cyclohexanone: a new-type azafulvenium reactivity of indole
The indole nucleus is a privileged heterocyclic scaffold, which is present in several natural
and synthetic compounds. New synthetic strategies to access functionalized indoles have …
and synthetic compounds. New synthetic strategies to access functionalized indoles have …