Leptin and leptin resistance in the pathogenesis of obstructive sleep apnea: a possible link to oxidative stress and cardiovascular complications

S Berger, VY Polotsky - Oxidative medicine and cellular …, 2018 - Wiley Online Library
Obesity‐related sleep breathing disorders such as obstructive sleep apnea (OSA) and
obesity hypoventilation syndrome (OHS) cause intermittent hypoxia (IH) during sleep, a …

Obstructive sleep apnoea and lipid metabolism: the summary of evidence and future perspectives in the pathophysiology of OSA-associated dyslipidaemia

M Meszaros, A Bikov - Biomedicines, 2022 - mdpi.com
Obstructive sleep apnoea (OSA) is associated with cardiovascular and metabolic
comorbidities, including hypertension, dyslipidaemia, insulin resistance and atherosclerosis …

The different clinical faces of obstructive sleep apnoea: a cluster analysis

L Ye, GW Pien, SJ Ratcliffe… - European …, 2014 - Eur Respiratory Soc
Although commonly observed in clinical practice, the heterogeneity of obstructive sleep
apnoea (OSA) clinical presentation has not been formally characterised. This study was the …

Changing faces of obstructive sleep apnea: treatment effects by cluster designation in the Icelandic Sleep Apnea Cohort

GW Pien, L Ye, BT Keenan, G Maislin, E Björnsdóttir… - Sleep, 2018 - academic.oup.com
Abstract Study Objectives Distinct clinical phenotypes of obstructive sleep apnea (OSA)
have been identified: Disturbed Sleep, Minimally Symptomatic, and Sleepy. Determining …

Differences in three-dimensional upper airway anatomy between Asian and European patients with obstructive sleep apnea

L Xu, BT Keenan, AS Wiemken, L Chi, B Staley… - Sleep, 2020 - academic.oup.com
Abstract Study Objectives This study evaluated differences in upper airway, soft tissues and
craniofacial structures between Asians from China and Europeans from Iceland with OSA …

Obesity as a risk factor for malignant melanoma and non-melanoma skin cancer

K Karimi, TH Lindgren, CA Koch, RT Brodell - Reviews in Endocrine and …, 2016 - Springer
The dramatic increases in incidence of both obesity and many cancers including skin cancer
emphasize the need to better understand the pathophysiology of both conditions and their …

Obstructive sleep apnea and asthma: associations and treatment implications

B Prasad, SM Nyenhuis, TE Weaver - Sleep medicine reviews, 2014 - Elsevier
Obstructive sleep apnea (OSA) and asthma are highly prevalent respiratory disorders and
are frequently co-morbid. Risk factors common to the two diseases include obesity, rhinitis …

Intermittent hypoxia and diet-induced obesity: effects on oxidative status, sympathetic tone, plasma glucose and insulin levels, and arterial pressure

E Olea, MT Agapito, T Gallego-Martin… - Journal of Applied …, 2014 - journals.physiology.org
Obstructive sleep apnea (OSA) consists of sleep-related repetitive obstructions of upper
airways that generate episodes of recurrent or intermittent hypoxia (IH). OSA commonly …

Role of leptin in obstructive sleep apnea

I Imayama, B Prasad - Annals of the American Thoracic Society, 2017 - atsjournals.org
Leptin is a peptide hormone produced mainly in white adipose tissue. It is known to regulate
energy homeostasis, inflammation, metabolism, and sympathetic nerve activity. Increasing …

Obstructive sleep apnea: personalizing CPAP alternative therapies to individual physiology

B Nokes, J Cooper, M Cao - Expert Review of Respiratory …, 2022 - Taylor & Francis
Introduction The recent continuous positive airway pressure (CPAP) crisis has highlighted
the need for alternative obstructive sleep apnea (OSA) therapies. This article serves to …