Role of oxidative stress in metabolic and subcellular abnormalities in diabetic cardiomyopathy

NS Dhalla, AK Shah, PS Tappia - International journal of molecular …, 2020 - mdpi.com
Although the presence of cardiac dysfunction and cardiomyopathy in chronic diabetes has
been recognized, the pathophysiology of diabetes-induced metabolic and subcellular …

The role of pro-inflammatory cytokines in the Pathogenesis of Cardiovascular Disease

H Zhang, NS Dhalla - International Journal of Molecular Sciences, 2024 - mdpi.com
With cardiovascular disease (CVD) being a primary source of global morbidity and mortality,
it is crucial that we understand the molecular pathophysiological mechanisms at play …

[HTML][HTML] Mechanisms for the development of heart failure and improvement of cardiac function by angiotensin-converting enzyme inhibitors

SK Bhullar, AK Shah, NS Dhalla - Scripta Medica, 2022 - scindeks.ceon.rs
Angiotensin-converting enzyme (ACE) inhibitors, which prevent the conversion of
angiotensin I to angiotensin II, are well-known for the treatments of cardiovascular diseases …

Future scope and challenges for congestive heart failure: moving toward development of pharmacotherapy

NS Dhalla, SK Bhullar, AK Shah - Canadian Journal of …, 2022 - cdnsciencepub.com
Heart failure is invariably associated with cardiac hypertrophy and impaired cardiac
performance. Although several drugs have been developed to delay the progression of …

[HTML][HTML] Alkaloid-rich extract of Lannea egregia leaf protect against cardiomyopathy in streptozotocin-induced type 2 diabetic rats

BO Ajiboye, IM Folorunso, KI Akinfemiwa… - Phytomedicine Plus, 2024 - Elsevier
Background Lannea egregia leaf has been used locally for the management of diseases
with limited scientific support. Hence, the cardiomyopathy protective ability of an alkaloid …

Mitochondrial dysfunction in fatal ventricular arrhythmias

W Wongtanasarasin, N Siri‐Angkul… - Acta …, 2021 - Wiley Online Library
Ventricular fibrillation (VF) and sudden cardiac arrest (SCA) remain some of the most
important public health concerns worldwide. For the past 50 years, the recommendation in …

Cardiac remodeling in chronic heart failure: pathophysiological implications

AK Shah, NS Dhalla - Pathophysiology, Risk Factors, and Management of …, 2024 - Elsevier
Chronic heart failure is invariably associated with adverse cardiac remodeling and
depressed cardiomyocyte function. The failing heart exhibits a wide variety of alterations in …

[PDF][PDF] Phytomedicine Plus

BO Ajiboye, IM Folorunso, KI Akinfemiwa, BE Oyinloye… - researchgate.net
Background: Lannea egregia leaf has been used locally for the management of diseases
with limited scientific support. Hence, the cardiomyopathy protective ability of an alkaloid …