Biointerface design for vertical nanoprobes

R Elnathan, MG Barbato, X Guo, A Mariano… - Nature Reviews …, 2022 - nature.com
Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …

Nano-bioelectronics

A Zhang, CM Lieber - Chemical reviews, 2016 - ACS Publications
Nano-bioelectronics represents a rapidly expanding interdisciplinary field that combines
nanomaterials with biology and electronics and, in so doing, offers the potential to overcome …

Shell microelectrode arrays (MEAs) for brain organoids

Q Huang, B Tang, JC Romero, Y Yang, SK Elsayed… - Science …, 2022 - science.org
Brain organoids are important models for mimicking some three-dimensional (3D)
cytoarchitectural and functional aspects of the brain. Multielectrode arrays (MEAs) that …

High‐aspect‐ratio nanostructured surfaces as biological metamaterials

SG Higgins, M Becce… - Advanced …, 2020 - Wiley Online Library
Materials patterned with high‐aspect‐ratio nanostructures have features on similar length
scales to cellular components. These surfaces are an extreme topography on the cellular …

Revealing neuronal function through microelectrode array recordings

MEJ Obien, K Deligkaris, T Bullmann… - Frontiers in …, 2015 - frontiersin.org
Microelectrode arrays and microprobes have been widely utilized to measure neuronal
activity, both in vitro and in vivo. The key advantage is the capability to record and stimulate …

Multi-electrode array technologies for neuroscience and cardiology

ME Spira, A Hai - Nature nanotechnology, 2013 - nature.com
At present, the prime methodology for studying neuronal circuit-connectivity, physiology and
pathology under in vitro or in vivo conditions is by using substrate-integrated microelectrode …

Vertical nanowire electrode arrays as a scalable platform for intracellular interfacing to neuronal circuits

JT Robinson, M Jorgolli, AK Shalek, MH Yoon… - Nature …, 2012 - nature.com
Deciphering the neuronal code—the rules by which neuronal circuits store and process
information—is a major scientific challenge,. Currently, these efforts are impeded by a lack of …

Advances in cell-conductive polymer biointerfaces and role of the plasma membrane

A Mariano, C Lubrano, U Bruno, C Ausilio… - Chemical …, 2021 - ACS Publications
The plasma membrane (PM) is often described as a wall, a physical barrier separating the
cell cytoplasm from the extracellular matrix (ECM). Yet, this wall is a highly dynamic structure …

Recent advances in three-dimensional microelectrode array technologies for in vitro and in vivo cardiac and neuronal interfaces

JS Choi, HJ Lee, S Rajaraman, DH Kim - Biosensors and Bioelectronics, 2021 - Elsevier
Three-dimensional microelectrode arrays (3D MEAs) have emerged as promising tools to
detect electrical activities of tissues or organs in vitro and in vivo, but challenges in achieving …

Iridium oxide nanotube electrodes for sensitive and prolonged intracellular measurement of action potentials

ZC Lin, C Xie, Y Osakada, Y Cui, B Cui - Nature communications, 2014 - nature.com
Intracellular recording of action potentials is important to understand electrically-excitable
cells. Recently, vertical nanoelectrodes have been developed to achieve highly sensitive …