Ferroptosis: a cell death connecting oxidative stress, inflammation and cardiovascular diseases

Y Yu, Y Yan, F Niu, Y Wang, X Chen, G Su, Y Liu… - Cell death …, 2021 - nature.com
Ferroptosis, a recently identified and iron-dependent cell death, differs from other cell death
such as apoptosis, necroptosis, pyroptosis, and autophagy-dependent cell death. This form …

Recent advances in hyperthermia therapy‐based synergistic immunotherapy

M Chang, Z Hou, M Wang, C Li, J Lin - Advanced Materials, 2021 - Wiley Online Library
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …

Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation

W Li, G Feng, JM Gauthier, I Lokshina… - The Journal of …, 2019 - Am Soc Clin Investig
Nonapoptotic forms of cell death can trigger sterile inflammation through the release of
damage-associated molecular patterns, which are recognized by innate immune receptors …

Cell death and immunity in cancer: from danger signals to mimicry of pathogen defense responses

AD Garg, P Agostinis - Immunological reviews, 2017 - Wiley Online Library
The immunogenicity of cancer cells is an emerging determinant of anti‐cancer
immunotherapy. Beyond developing immunostimulatory regimens like dendritic cell‐based …

Origin and consequences of necroinflammation

M Sarhan, WG Land, W Tonnus… - Physiological …, 2018 - journals.physiology.org
When cells undergo necrotic cell death in either physiological or pathophysiological settings
in vivo, they release highly immunogenic intracellular molecules and organelles into the …

The pathological features of regulated necrosis

W Tonnus, C Meyer, A Paliege… - The Journal of …, 2019 - Wiley Online Library
Necrosis of a cell is defined by the loss of its plasma membrane integrity. Morphologically,
necrosis occurs in several forms such as coagulative necrosis, colliquative necrosis …

Damage-associated molecular patterns in myocardial infarction and heart transplantation: the road to translational success

MJM Silvis, SE Kaffka genaamd Dengler… - Frontiers in …, 2020 - frontiersin.org
In the setting of myocardial infarction (MI), ischemia reperfusion injury (IRI) occurs due to
occlusion (ischemia) and subsequent re-establishment of blood flow (reperfusion) of a …

Necroptosis triggers spatially restricted neutrophil-mediated vascular damage during lung ischemia reperfusion injury

W Li, Y Terada, YY Tyurina, VA Tyurin… - Proceedings of the …, 2022 - National Acad Sciences
Ischemia reperfusion injury represents a common pathological condition that is triggered by
the release of endogenous ligands. While neutrophils are known to play a critical role in its …

Regulation of cytokine production by the unfolded protein response; implications for infection and autoimmunity

JA Smith - Frontiers in immunology, 2018 - frontiersin.org
Protein folding in the endoplasmic reticulum (ER) is an essential cell function. To safeguard
this process in the face of environmental threats and internal stressors, cells mount an …

Danger-associated molecular patterns (DAMPs): the derivatives and triggers of inflammation

S Patel - Current allergy and asthma reports, 2018 - Springer
Abstract Purpose of Review Allergen is an umbrella term for irritants of diverse origin. Along
with other offenders such as pathogens, mutagens, xenobiotics, and pollutants, allergens …