In this Minireview, the importance and implementation of green chemistry practices in the
pharmaceutical industry are illustrated. With notable examples, some of the most important …

Indoline is an important structural motif present in several biologically active compounds
from both natural and synthetic origins. The occurrence of this heterocyclic unity in these …

Chemotherapy has been a standard intervention for a variety of cancers to impede tumor
growth, mainly by inducing apoptosis. However, development of resistance to this regimen …

The synthesis of novel pyrazolo [3, 4-h] quinoline-3-carbonitriles has been achieved through
a one-pot, four-component domino strategy under solvent-free microwave conditions. One of …

Tetrahydroquinoline (THQ) is an important structure for synthesizing multiple biologically
active derivatives. Thus, we developed new quinoline derivatives and investigated them as …

A series of lH-pyrazolo [3, 4-b] quinolin-3-amine derivatives were synthesized and evaluated
for anticancer efficacy in a panel of ten cancer cell lines, including breast (MDAMB-231 and …

Over the past two decades, functionalized quinolines have attracted much attention due to
their considerable biological and pharmacological activities as antiasthmatic, 1 antibacterial …

The focus of this review is on the synthetic routes available for different types of
pyrazoloquinoline derivatives. There are three types of synthetic methods: i) from pyrazole …

Abstract Variously substituted isoxazolo [5, 4-c] quinolines can be easily prepared in high
yields by Pd-catalyzed heteroannulation of 5-carbonyl-4-haloisoxazoles with 2 …

A practical and straightforward access to pyrazolo [3, 4-c] quinolines by molecular sieve
mediated dehydrogenative [2+ 2+ 1] heteroannulation of N-(o-alkenylaryl) imines with …