[HTML][HTML] Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder

N Eissa, M Al-Houqani, A Sadeq, SK Ojha… - Frontiers in …, 2018 - frontiersin.org
Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …

[HTML][HTML] Serotonin-related rodent models of early-life exposure relevant for neurodevelopmental vulnerability to psychiatric disorders

TS Adjimann, CV Argañaraz, M Soiza-Reilly - Translational psychiatry, 2021 - nature.com
Mental disorders including depression and anxiety are continuously rising their prevalence
across the globe. Early-life experience of individuals emerges as a main risk factor …

Impaired repair of DNA damage is associated with autistic-like traits in rats prenatally exposed to valproic acid

M Servadio, A Manduca, F Melancia, L Leboffe… - European …, 2018 - Elsevier
Prenatal exposure to the antiepileptic and mood stabilizer valproic acid (VPA) is an
environmental risk factor for autism spectrum disorders (ASD), although recent …

Involvement of phosphodiesterase 2A activity in the pathophysiology of fragile X syndrome

T Maurin, F Melancia, M Jarjat, L Castro, L Costa… - Cerebral …, 2019 - academic.oup.com
The fragile X mental retardation protein (FMRP) is an RNA-binding protein involved in
translational regulation of mRNAs that play key roles in synaptic morphology and plasticity …

Prenatal exposure to valproic acid is associated with altered neurocognitive function and neurogenesis in the dentate gyrus of male offspring rats

T Kinjo, M Ito, T Seki, T Fukuhara, K Bolati, H Arai… - Brain research, 2019 - Elsevier
In pregnant women with epilepsy, it is imperative to balance the safety of the mother and the
potential teratogenicity of anticonvulsants, which could cause impairments such as …

[HTML][HTML] Autism spectrum disorders: Autonomic alterations with a special focus on the heart

BA Ellenbroek, HK Sengul - Heart and Mind, 2017 - journals.lww.com
Autism spectrum disorders (ASD) is a heterogeneous group of developmental disorders
characterized by stereotyped behaviors and thoughts, and deficits in social behavior …

Timing and intertemporal choice behavior in the valproic acid rat model of autism spectrum disorder

WE DeCoteau, AE Fox - Journal of Autism and Developmental Disorders, 2022 - Springer
Recently it has been proposed that impairments related to autism spectrum disorder (ASD)
may reflect a more fundamental disruption in time perception. Here, we examined whether in …

Uso y efectividad de antipsicóticos atípicos en el trastorno del espectro autista

LA Ortega-Pineda, L Fernández-Cañedo… - Revista …, 2023 - eneurobiologia.uv.mx
El trastorno del espectro autista (TEA) pertenece al grupo de trastornos del neurodesarrollo.
De acuerdo con la quinta edición del Manual diagnóstico y estadístico de desórdenes …

[HTML][HTML] Intact maternal buffering of stress response in infant rats despite altered responsivity towards maternal olfactory cues in the valproic acid model of autism-like …

AM White, X An, J Debiec - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
Disrupted processing of social cues and altered social behaviors are among the core
symptoms of autism spectrum disorders (ASDs), and they emerge as early as the first year of …

Neurochemical mechanisms of pathogenesis and pharmacological correction of autism spectrum disorders: current concepts and prospects

AA Alymov, IG Kapitsa, TA Voronina - Neurochemical Journal, 2021 - Springer
The presence of a significant and constantly growing global prevalence of autism spectrum
disorders (ASD) coupled with the ongoing search for optimal drugs and treatments has …